Brandon Bongers

Hello! I am happy to share my (Open Access) review: "Proteochemometrics – recent developments in bioactivity and selectivity modeling" at sciencedirect.com/science/articl… It touches upon recent PCM advances in several areas; including deep learning, bioactivity and selectivity. Thanks!

Today Dr. @BongersBrandon defended his PhD thesis entitled: "The flux and flow of data" (containing several oublished chapters including : jcheminf.biomedcentral.com/articles/10.11… ) Congratulations Brandon and thanks to the committee! CC @LACDR @LeidenScienceEN

@CDDLeiden at #shef2023 Good times, good science..!

The latest by our group: an application note about DrugEx. Integrated, streamlined, with API and openly available..! Fully compatible with the GenUI interface, and for download on our github: github.com/CDDLeiden/Drug… #OpenAccess paper: pubs.acs.org/doi/10.1021/ac…

The latest: PCM Identifies Chemically Diverse Norepinephrine Transporter Inhibitors (by @BongersBrandon , @PBRHartog , et al). First ever data driven selection to identify the optimal # of targets in a PCM model. pubs.acs.org/doi/10.1021/ac… CC: @LED3hub @LeidenScienceEN @LACDR

Work by @BongersBrandon, @m_gorostiola and colleagues @CDDLeiden shows that mutations found in G Protein-coupled receptors related to cancer are weakly correlated to specific domains in the protein or functional conservation nature.com/articles/s4159…

Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based #VirtualScreening #drugdesign pubs.acs.org/doi/10.1021/ac… @ATuerkova @BongersBrandon @GJPvWesten @BZdrazil #vol62 #issue24 #JCIM #MachineLearning #DeepLearning

Work by @OlivierBeqgn , @BongersBrandon , @Willemjespers , @GJPvWesten et al. :” Papyrus: a large-scale curated dataset aimed at bioactivity predictions” Get the data here: doi.org/10.5281/zenodo… Scripts to adapt your own data: github.com/CDDLeiden/Papy… jcheminf.biomedcentral.com/articles/10.11…

Work by @BongersBrandon, @m_gorostiola and colleagues @CDDLeiden shows that mutations found in G Protein-coupled receptors related to cancer are weakly correlated to specific domains in the protein or functional conservation nature.com/articles/s4159…

@CDDLeiden @Willemjespers @GJPvWesten @BongersBrandon @m_gorostiola @NWO_Science @LACDR @LED3hub @LeidenScience Also made possible by @oncodeinstitute

New research online! Some computational optimisation and entropy analysis looking into mutations! Very happy how this turned out, thank you to the co-authors (and especially @m_gorostiola)

This is my @Spotify Wrapped #SpotifyWrapped! open.spotify.com/wrapped/share/… A long year, where I felt I needed music more than anything to keep me going. As always, love you all, and take care of yourself.

Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by #MachineLearning-Based #VirtualScreening #AI #DrugDesign #drugdiscovery pubs.acs.org/doi/10.1021/ac… @ATuerkova @BongersBrandon @GJPvWesten @BZdrazil #JCIM #ASAP

@GJPvWesten MY LIFE FOR AIUR!

Not bad... #zinin

Thank you for a great time, and until I see you all again.

Finally, it was also the last thing I did as an official PhD graduate. I will be spending the next few weeks to wrap everything nicely up for my thesis and collaborations before moving on. Hopefully I will find a job to start after the summer - as a data analyst preferably.

Had a great and interesting time at @intconfchemstr. It was lovely to present my work alongside so much captivating research. Hats off to the organizers for a very smooth experience. The manuscript presented is currently in revision, but will hopefully be presentable soon.

Thanks to all the participants for a great conference.. Save the date for 2025 (June 1st - June 5th)..! #ICCS2025

The amazing #2022ICCS is over. The @cddleiden delegation also had posters from: @BournezC , @martin_sicho , @ManuelG81702324 , @sohvi_luukkonen , @DavidAraripe , @1inde1 , @BolaK_DDD , @BongersBrandon , Helle vd Maagdenberg, Rosan Kuin. CC @LeidenScienceEN , @LACDR #2022ICCS