Brian Paegel

I am seeking a postdoctoral fellow to work on drug discovery technology development (DNA-encoded libraries, solid-phase synthesis, tissue printing, polymer chemistry, cellular assay development, and microfab/microfluidics). Send a CV and cover letter if interested!

Methylate to degrade, @TheAlbrecht_Lab? I'm interested.

@TheAlbrecht_Lab @carointhelab @LJSeabrook Make it more degrader!

Ever wondered how lysosomes and vitamins are talking to each other? And whose MrDegron?? You won’t wanna miss first time ASCB presenters @carointhelab @LJSeabrook THIS Sunday, Dec 3 1:45 #cellbio2023 #autophagy

Fab work from @TheAlbrecht_Lab showing B6 levels regulated by novel degradation of PDXK. Congrats team! 🎉

@TheBickerLab I’m suspicious already. Do I even know you????

I generally take student evaluation criticisms to heart and reflect on how I could improve, but I'm standing my ground here. "Dr. Bicker's disapproval of salt and vinegar chips really made me question his character and qualifications. Must be an Ohio thing."

@doc_jlmeier No BRD4DAYZ?

@SpitaleLab Congrats y’all! 🔥

Oh, hey, look. Using 5' 32 P-labeled Primer and Reverse Transcription to Probe RNA Structure pubmed.ncbi.nlm.nih.gov/37471570/

@JessenLab Not enough phosphorus atoms here!

Thanks to fabulous collaborators Christian Cunningham and Alix Chan 🧬@genentech🧬 and bead-tastic long-time scientific associate 🔵🔵🟠🔵@valcavett. This was a dream on paper not too long ago! 🎶Don't~stop~believin'~🎶 @UCI_SPPS

I'm sure there will be many more applications. See our first app with @ChaputLab looking at xeno nucleic acids! pubs.acs.org/doi/10.1021/ac…

What goes better with @UCIrvine than boba? Standard magnetic microbeads can template unusually uniform gel particles just by bulk emulsification. Lots of potential apps, but this paper details a super nifty one: proximity-driven biochemical synthesis! pubs.acs.org/doi/10.1021/ac…

@scarletjpark Big congrats! Where to next?

1) I’m a doctor now 2) I have the coolest graduation gift (it’s a D. mel puzzle)

@disney_lab @ChaputLab pulling hard for "X"

Another collaboration with the amazing @BrianDNA who needs to change a letter in his Twitter handle!

grateful to contribute this paper in memory on the incomparable Richard Lerner, the leader of scripps - RIP Richard! DNA‐Encoded Libraries and Their Application to RNA - Yang - Israel Journal of Chemistry - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10…

Welcome to @UCIrvine, Trader Lab!

@DJTraderLab @UCI_SPPS Welcome, you amazing new anteaters! Zot zot zot!

We’re here for the party (and some science too) @UCI_SPPS

@matoseviclab @chadtough Congratulations! 🎉

So honored to receive this New Investigator award from @chadtough! Incredibly exciting to join a stellar group of scientists and have the opportunity to advance research into new therapies for DIPG! #chadtough #dipg

@tfmPhD Well that doesn’t sound awesome…

@RobertoZoncu @HijaiShin @CRI_UTSW Fabulous news! Congrats both!

Thrilled and super-proud of Regina @HijaiShin , who will soon open her own lab at @CRI_UTSW ! Regina is a phenomenal scientist, dedicated mentor, wonderful colleague, and I can't wait for the fantastic science to come out of the Shin lab!