Center for Antibody Technologies

A promising #snake venom #antibody that failed testing is good news for developing a broad-spectrum #antidote. New research from i.a. Danish & Costa Rican scientists in @NatureComms. @CAT4Science @UniversidadCR @AndreasLaustsen @CVSoerensen #Immunology dtu.dk/english/newsar…

Thanks to all collaborators and funders including @DTUtweet @DTUbioengineer @DTUBiosustain @wellcometrust @VILLUMFONDEN @novonordiskfond @ERC_Research @UniversidadUCR

Exciting News! - Yesterday our newest paper was published in @NatureComms by @CVSoerensen, @AndreasLaustsen and many more. The study unveils highly surprising research findings on snakebite envenoming therapies that call for caution. Full study: nature.com/articles/s4146…

Thanks to Michael Hust and Theam Soon for making us part of this, to @CAT4Science team, @DTUbioengineer, @DTUtweet, @AndreasLaustsen for your support, to employees at @BioInvent and @mats_ohlin for the fruitful discussions, and @wellcometrust and @ERC_Research for funding!

Typically, #whole cell selections result in discovery of antibodies against highly expressed cell surface receptors. Here, we present detailed protocols on phage display selections, utilizing #depletion or #blocking, for discovery of #rare #antibodies against multiple targets.

We are happy to share the publication of a new book on #phage display in @SpringerNature, where Tulika and @AnneLjungars describe #deep mining methods for the discovery of #rare #antibodies. link.springer.com/book/10.1007/9…

The sun is shining in Denmark and besides our passion for science we also love and enjoy moments together by having a barbecue or flowing down the river on a canue! Have a look at some of our moments together 😊

🔬🌍 Exciting PhD Opportunities in #DataScience and #Biosustainability at @DTUtweet lnkd.in/gxScbC62

Podcast: A few months ago, I had the pleasure of doing this @REBBLS Podcast with @JornEmborg, where I got to tell about my career as both an #academic and #biotech #entrepreneur, as well as how to bridge these two worlds: open.spotify.com/episode/44mo5H…

Further, we thank @DTUtweet, @DTUbioengineer,@VILLUMFONDEN, @wellcometrust, @ERC_Research for the support to realize this project.

Last week @jack_wade6 successfully defended his PhD thesis about "Engineering and structural characterization of cross reactive, pH sensitive antibodies against long chain alpha-neurotoxins". Thank you for the last three years and we wish you can continue your successful path!🥳

We are happy to share a new paper in @CellRepMethods by @AnneLjungars about her previous work at @BioInvent and @lunduniversity regarding #antibodydiscovery using #computational modeling combined with #antibody #phage display and #NGS shorturl.at/oAJ34

We have prepared a thread about our new #preprint about pH-dependent binding antibodies and how cool this is on #antivenom development. Thanks to @ERC_Research for the generous funding and to all our colleagues @DTUtweet @DTUbioengineer @Oslounivsykehus shorturl.at/beEY9

Thank you @DTUbioengineer @AndreasLaustsen @LLedsgaard @markthebanana @AndersenJT and @CAT4Science team for your help with this study! 🧬🥽

Our study shows that histidine doping may not always be necessary to achieve pH-dependency in antibodies. Plus, given the high diversity available in a naïve antibody library, it can likely be applied to discover pH-dependent antibodies against a wide range of antigens!

We are excited to share our #preprint “Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library”! Read: biorxiv.org/content/10.110…