CBU

New pre-print out! 🎉 With Mathilde + team we traced spatio-temporal shifts in genetically regulated #transcription across 10,000 years of Western Eurasia, fine-mapping regulatory features targeted by #selection! 👉 doi.org/10.1101/2025.1… ! #popgen #genomics

Polygenic and developmental profiles of autism differ by age at diagnosis nature.com/articles/s4158…

Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions nature.com/articles/s4158…

Multiple overlapping binding sites determine transcription factor occupancy nature.com/articles/s4158…

Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci sciencedirect.com/science/articl…

The Importance of Regulatory Network Structure for Complex Trait Heritability and Evolution academic.oup.com/mbe/article/42…

Whole-genome sequencing of 490,640 UK Biobank participants nature.com/articles/s4158…

Single-cell eQTL mapping of human endogenous retroviruses reveals cell type-specific genetic regulation in autoimmune diseases nature.com/articles/s4146…

Towards improved fine-mapping of candidate causal variants nature.com/articles/s4157…

And more posters at #eshg today! Meet Daniela and Davide at P18.116C and P21.001C in the coming session, and Roberta at P21.022D later today!

Are you at #eshg2025 in Milan? Come and check out what we are up to! 3 posters from our group in the coming session: Camilla at P18.011.B, Irene at P18.016B and Ettore at P18.131B!

Our work on the molecular basis of the genetic correlation between BMI and brain morphology has now appeared in PLOS Genetics journals.plos.org/plosgenetics/a… Thanks to @DFusco17, @CamillaMarinel8, @MathildeAndr11, @LuciaTroiani, Martina Noè, and @FabrizioPi1139

Genetically regulated eRNA expression predicts chromatin contact frequency and reveals genetic mechanisms at GWAS loci nature.com/articles/s4146…

An atlas of single-cell eQTLs dissects autoimmune disease genes and identifies novel drug classes for treatment sciencedirect.com/science/articl…

Plasma proteome variation and its genetic determinants in children and adolescents nature.com/articles/s4158…