Cindy Fonseca retweetledi

Happy to share our latest work describing specific dependencies of CIN tumor cells on KIF18A. This complements two recent studies from Uri Ben-David and @GanemLab, which identify vulnerabilities of tumor cells with abnormal chromosome numbers 1/5
Nature Communications@NatureComms
Kinesin motor protein, KIF18A, permits the proliferation of chromosomally unstable cells and KIF18A knockdown induces centrosome fragmentation. nature.com/articles/s4146… #CancerResearch @jstumpffVT @UVMLarnerMed @UVMcancercenter
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