CRC 1430

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CRC 1430

CRC 1430

@crc1430

DFG funded Collaborative Research Centre 1430 "Molecular Mechanisms of Cell State Transitions" @unidue @unidue_zmb

Katılım Mayıs 2021
105 Takip Edilen138 Takipçiler
CRC 1430
CRC 1430@crc1430·
Due to recent events, we moved to 🦋 @crc1430.bsky.social
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CRC 1430
CRC 1430@crc1430·
Wrapping up the year with our @crc1430 Female Scientist Get-Together Christmas Special! 🎄✨ At the Christmas Market, we’ll revisit this year’s highlights and brainstorm new topics for 2025. 👩‍🔬 Here’s to another year of connection and growth! #WomenSupportWomen #Networking #STEM
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CRC 1430
CRC 1430@crc1430·
Congrats to @MalteGersch and the @GerschLab on their new publication in Nature Chemical Biology @nchembio! 🎉 Fantastic work on #USP53 #DUB #ChemicalBiology! 🔗 nature.com/articles/s4158
Malte Gersch@MalteGersch

Very excited to share that our manuscript on the "Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53" was published today at Nature Chemical Biology @nchembio. Congratulations Kim, Kai, and all authors! nature.com/articles/s4158…

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CRC 1430
CRC 1430@crc1430·
Tomorrow, November 26, we are looking forward to hosting @georg_e_winter from @CeMM_News, Austrian Academy of Sciences, Vienna, at @crc1430 @unidue. Join us for his exciting talk on small-molecule degraders!
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CRC 1430
CRC 1430@crc1430·
We’re happy to welcome Gertrudis Rojas from the Center of Molecular Immunology (CIM), La Habana, Cuba, to @crc1430 @unidue tomorrow, Nov 19. Join us for her exciting talk: "Phagekine directed evolution: guiding the power of the immune system with tailor-made immunomodulators."
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CRC 1430
CRC 1430@crc1430·
Today‘s @crc1430 female scientist get-together was all about real stories and practical advice! 💫Special thanks to our guest Manuela Kowalczyk for sharing her experiences and sparking insightful discussions on navigating a career in #STEM 👩‍🔬#WomenSupportWomen #Networking
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CRC 1430@crc1430·
Excited to share a new paper from @GolgiLabEssen, published in @RoySocChem: 'Induced degradation of SNAP-fusion proteins'! A great collaboration within @CRC1430 with #KaiserLab and #ACE!! #SNAPPROTACs #FantasticCollaboration
Lana Buzuk@L_Buzuk

🚨 Publication alert from the Hellerschmied Lab‼️ Interested in adding SNAP-PROTACs to your molecular toolbox? Then take a read! Congratulations to all the authors on this exciting work! @GolgiLabEssen @unidue_zmb @crc1430 pubs.rsc.org/en/content/art…

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CRC 1430@crc1430·
Congrats to @CRC1430 members from @GerschLab @MalteGersch on their new @biorxivpreprint! Fantastic work on USP30 inhibition via chimeric deubiquitinase engineering and DUB ligandability. Check it out! #USP30 #DUB #StructuralBiology
Malte Gersch@MalteGersch

Interested in Ubiquitin, Parkinson’s disease therapy, mitochondria or DUB inhibitors? This preprint may be for you: We show how the deubiquitinase USP30 can specifically be inhibited & introduce a framework for DUB ligandability. biorxiv.org/content/10.110… Thread👇 – with movie!!

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CRC 1430@crc1430·
We are excited to announce the new publication from our @CRC1430 members @hemmo_lab in @PNASNews: #VCPp97 regulates PP1 beyond biogenesis! Fantastic work by the team! #Biochemistry #Research #FRET
HemmoMeyerLab@hemmo_lab

Out in PNAS: #VCPp97 regulates PP1 beyond biogenesis! It maintains a steady-state between a thermodynamic sink for PP1 and active holophosphatases. Great work by Anja et al. using FRET and reconstituting PP1 holophosphatase formation. In vitro veritas. pnas.org/doi/10.1073/pn…

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CRC 1430@crc1430·
Congratulations to our @CRC1430 members @GatsogiannisLab on their new lab preprint @biorxiv! This work reveals unprecedented aspects of the elevator-type transport mechanisms of the UapA purine transporter. #HighResolution #CryoEM #Research
Gatsogiannis Lab@GatsogiannisLab

📢New lab preprint: 2.05 A #cryoEM structure of UapA: unprecedented aspects of the elevator-type transport (incl. water, lipids) and regulatory roles of the N-tail. With Diallinas, Mikros labs. Kudos @broutzakis and all co-authors. @uni_muenster #SoN biorxiv.org/content/10.110…

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CRC 1430@crc1430·
We're thrilled to announce a new preprint from our @CRC1430 member @MalteGersch and the @GerschLab on two novel active DUBs and a unique type of DUB activity! Check it out! #Deubiquitinases #ChemicalBiology #Research
Malte Gersch@MalteGersch

For all ubiquitin, deubiquitinase and chemical biology aficionados: Here's a preprint from the lab introducing 2 new active DUBs in humans & a unique type of DUB activity one would miss with the widely used panels of free ubiquitin chains. t.ly/GnRVv Thread👇(1/10)

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CRC 1430@crc1430·
We’re excited to highlight the work of @MartinPSchwalm, our @CRC1430 member from the Knapp Lab, and colleagues on the functional characterization of pathway inhibitors for the ubiquitin-proteasome system (UPS) as tool compounds for CRBN! #Ubiquitin #Proteasome #Biochemistry
biorxiv_biochem@biorxiv_biochem

Functional characterization of pathway inhibitors for the ubiquitin-proteasome system (UPS) as tool compounds for CRBN and ... biorxiv.org/cgi/content/sh… #biorxiv_biochem

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CRC 1430@crc1430·
Proud of our @crc1430 PhD students for their exciting talks and the engaging scientific discussions at this year's PhD symposium. Thank you to everyone who made this event a tremendous success! #PhDResearch #ScienceInAction
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CRC 1430@crc1430·
On September 18th, our @crc1430 Female Scientists Get-Together returns! 💬✨ Every six weeks, this #WomenInScience event provides a valuable platform for our female members to exchange strategies and discuss career development. #Networking #WomenInSTEM
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Keşfet

@MalteGersch @nchembio @CeMM_News @unidue @Saar_Uni @iden_lab @FrontiersIn @GolgiLabEssen