Center for Musculoskeletal Research

Thank you to our keynote speakers @AlisonBoyceMD and Sundeep Khosla! That’s a wrap on our 2024 symposium!

What a great way to end our symposium! Sundeep Khosla took us on a tour of his group’s extensive body of work in his keynote presentation entitled “Sympathetic tone and cellular senescence: Leveraging integrative physiology for new osteoporosis treatments”

@BethBragdon closing out the selected oral abstract session with a thought-provoking presentation on “Defining Stem Cell Activation following Fracture”

Great science continues! We just heard from Tadatoshi Sato in his talk entitled “Recombinant AAV9-mediated gene editing in Osteogenesis Imperfecta” 🦴 🧬 ✂️

The high bar set by our morning talks continues! @gabbygilmer walked us through an impressive body of work in “Loss of estradiol and progesterone with menopause drives cartilage degeneration via chondrocyte senescence and extracellular matrix disassembly”

Sihan Liu kicking off our afternoon session with a great presentation on “Macrophage-derived Wnt5a Promotes Osteoarthritis by Disrupting T cell Balance”

Poster session in full swing at the 9th Annual Musculoskeletal Research Symposium. With 59 posters, there is a lot to discover! RT and let us know whose poster you visited or one cool thing that you learned. ⬇️

Our first keynote presentation: “Fibrous Dysplasia/McCune-Albright Syndrome: Interplay of osteoclast/osteoblast function” @AlisonBoyceMD presented her incredible work in FD that has generated great conversation during the Q&A!

Byron Chan (MGH) closes the morning oral abstract presentations session with “Ebf3-expressing osteoblast progenitors contribute to homeostatic bone remodeling and intermittent parathyroid hormone-induced bone formation” @NIH_NIAMS

Another fantastic presentation by Jakob Hoeppner from MGH: “Unravelling the Pathophysiology of Eiken Syndrome: Deciphering the Role of the PTH Receptor's C-Tail in Enchondral Ossification and Bone Mineral Homeostasis” @NIH_NIAMS

Jared Whitlock from NICHD kicking off the Musculoskeletal Research Symposium’s oral abstract presentations with “Getting to the "wrong" place at the right time: A Redox switch directs La protein to the osteoclast surface, promoting multinucleation and bone resorption” @NIH_NIAMS

Excited to kick off a full day of exciting musculoskeletal research! ⁦@CSR_MGH⁩ ⁦@NIH_NIAMS⁩

A wonderful Q&A with Ridhima Seth after she presented “PTH signaling in Ctsk+ lineage cells is critical for skeletal homeostasis and tooth formation and eruption”

Kicking off the 9th Annual Musculoskeletal Research Symposium with over 29 institutions represented from the New England area!

This Monday at 9am: 9th Annual Musculoskeletal Research Symposium! Location: MGB Assembly Row 399 Revolution Dr, Somerville, MA 02145. Register today using this link: csr-mgh.org/event/csr-musc… We look forward to the keynotes by Alison Boyce, MD (NIH) and Sudneep Kholsa, MD (Mayo)

This Wednesday 11/8: CSR Journal Club @4pm. Dr. Vagheesh Narasimhan presents “The genetic architecture and evolution of the human skeletal form”

LOI due today at 5p: RFA for NIAMS-funded Center of Research Translation on Osteoporosis Bone Anabolic Therapies (CORT) Pilot & Feasibility Award ($30,000/year direct costs). Email dafitzgerald@mgb.org for details. More information: csr-mgh.org/wp-content/upl…… @MGH_RI

RFA for NIAMS-funded Center of Research Translation on Osteoporosis Bone Anabolic Therapies (CORT) Pilot & Feasibility Award ($30,000/year direct costs). LOI due 9/15 at 5pm. Email dafitzgerald@mgb.org for details. More information: csr-mgh.org/wp-content/upl… @MGH_RI

New academic year, 2023-2024 Massachusetts General Hospital Calcium Rounds (hybrid) launching Thursday morning 9:05 at Thier 10. First lecture of the year by Dr Hank Kronenberg: "Overview of Calcium and Phosphate Homeostasis". @EndocrineMGH @MGHMedicine @MGH_RI @MGHBoneResearch

Tomorrow at 4pm: CSR Summer Lecture Series “Osteoarthritis and Rheumatoid Arthritis” by Jae-Hyuck Shim, PhD and Li Zeng, PhD. Email CSRmail@partners.org for Zoom link!