Cécile Lesueur
27 posts
#GPMelt users, it was fantastic meeting so many of you at my #HUPO2024 poster!🎊 As discussed, the revised GPMelt code is now on GitLab. Also, check out the GPMelt website to dive into the model—no advanced maths required! 💻🔍 #Proteomics
All links here: linktr.ee/CecileCADS
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What a wonderful experience chairing a AI and Bioinformatics Approaches session in the plenary hall at #HUPO2024 yesterday! Big thanks to the organizers for giving me this opportunity, to the speakers for their excellent talks, and to Nuno Bandeira for chairing with me!
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Thrilled to see my PhD work published! 🪇 Check out GPMelt, our new framework for uncovering the dark meltome of TPP datasets @savitski_lab @MagnusRattray. Discover how we’re pushing the boundaries of thermal proteome profiling!
See the implementation: git.embl.de/grp-savitski/g…
EMBL@embl
EMBL scientists developed GPMelt, a method to explore proteins with unconventional melting behaviors, previously overlooked in Thermal Proteome Profiling (TPP). By embracing the full complexity of the meltome, GPMelt enables new biological discoveries. journals.plos.org/ploscompbiol/a…
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Cécile Lesueur retweetledi
Great to see our work out this week in JACS @kaydanych @Prevedel_Lab @claire_deo Hopefully just the start of a wave of photoacoustic probe development to complement existing neuroimaging tools!
pubs.acs.org/doi/10.1021/ja…
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Cécile Lesueur retweetledi
Cécile Lesueur retweetledi
Very happy to share that our work, with @kaydanych @Prevedel_Lab @claire_deo, developing the first chemigenetic probes and calcium sensors for photoacoustic imaging is out now on biorxiv ! biorxiv.org/content/10.110…
Heidelberg, Germany 🇩🇪 English
Cécile Lesueur retweetledi
TPP goes subcellular! We are happy to present the preprint from our lab introducing mito-TPP, an optimized TPP workflow that enables the direct application of TPP on isolated mitochondria for the direct and extensive study of the mitochondrial proteome. biorxiv.org/content/10.110…
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Cécile Lesueur retweetledi
Presented our work on photoacousitc calcium probes at @PhotonicsWest with @claire_deo @alexcook8997 and @Prevedel_Lab!
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9/ To all GPMelt users: the user-friendly version of the code is in the process of being made available, just be a bit more patient ;) And I’m happy to answer any questions about TPP analysis using GPMelt!
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8/ GPMelt thus opens the way to exciting proteomic discoveries of which you can be the instigator!
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Interested in diving into the dark side of the meltome to uncover new biology regarding protein interactions, localisation and functions? Check out GPMelt, our new statistical framework extending the analysis of Thermal Proteome Profiling experiments! @MagnusRattray @savitski_lab
bioRxiv Bioinfo@biorxiv_bioinfo
Hierarchical Gaussian process models explore the dark meltome of thermal proteome profiling experiments. biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
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