Celixir

Nobel Prize Winner - Professor Sir Martin Evans is the co-founder of @CelixirLtd #stemcells #nobelprizewinner #regenerative #medicine #science #news

A fascinating read about a promising cell therapy for RPE (Retinal Pigment Epithelium) degeneration such as in age related macular degeneration. nature.com/articles/s4159…

An interesting article discussing a newly formed joint undertaking in Morphological Profiling with Cell Painting genengnews.com/topics/drug-di…

This study looks at investigating karyotype and genome size of tick cell lines. nature.com/articles/s4159…

This interesting study looks at aiming to repair pathogenic allele-specific single-nucleotide mutations using a single round of genome editing. nature.com/articles/s4159…

The European Medicines Agency (EMA) has agreed to review a request to approve the investigational CAR T-cell therapy, lisocabtagene maraleucel (liso-cel), for people with pretreated lymphomas. immuno-oncologynews.com/2020/07/22/ema…

CAR T-cell therapy, Tecartus, granted FDA approval for Mantle Cell Lymphoma immuno-oncologynews.com/2020/07/28/car…

CAR-T cells are promising for the treatment of cancer but their side effects are a concern. In this study, a team has developed a new CAR T-cell immunotherapy strategy that uses light to activate the immune cells specifically in cancerous regions. immuno-oncologynews.com/2020/07/24/lig…

The long-term effects of immune checkpoint inhibitors, PD-1 and PD-L1 inhibitors, in cancer treatment are encouraging esmo.org/oncology-news/…

Recombinant canstatin seems to reduce heart damage after heart attacks. nature.com/articles/s4159…

Scorpion toxins may be helpful in treating heart attacks. sciencedaily.com/releases/2020/…

3D printing allows the formation of a working heart pump from human heart cells and is another step towards artificial hearts. sciencedaily.com/releases/2020/…

Eating lots of protein, especially plant protein, is associated with a lower risk of death from any cause. sciencedaily.com/releases/2020/…

This study shows the safety and efficacy of dopaminergic progenitors (DAPs) derived from a clinical-grade human iPSC line. These cells have the potential to replace damaged neurons in Parkinson’s disease. nature.com/articles/s4146…

This study identifies roles of autophagy in embryonic stem cell renewal and differentiation and presents an opportunity for new regenerative medicines. regmednet.com/process-of-ste…

This review discusses using humanized mice to test anti-cancer therapies. mdpi.com/2072-6694/12/7…

An interesting approach to bone implant biomaterials. nature.com/articles/s4159…

A brief discussion of the essential safety considerations for cell and gene therapies. biopharma-excellence.com/news/2020/7/3/…

A nice summary of terminology relating to advanced therapy medicinal products (ATMPs), including gene and cell-based therapies, tissue-engineered products, and combined ATMPs. raps.org/news-and-artic…

The U.S. Food and Drug Administration (FDA) restarting on-site inspections based on a COVID-19 Advisory Rating system (COVID-19 Advisory Level). gmp-compliance.org/gmp-news/inspe…

The Medicines and Healthcare products Regulatory Agency (MHRA) is making careful preparations for a safe return to normal UK on-site Good Practice (GxP) inspection scheduling. mhrainspectorate.blog.gov.uk/2020/07/23/mhr…