Chandan K Sen

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Chandan K Sen

Chandan K Sen

@ChandanKSen

https://t.co/IpTzPQdvqz

Pittsburgh, PA Katılım Mayıs 2020
7 Takip Edilen216 Takipçiler
Chandan K Sen
Chandan K Sen@ChandanKSen·
This gift of chocolates arrived from colleagues in Ukraine — sent from a nation at war. Дякую for the sweetness, and for your resilience. Your courage and commitment to science inspire us all. Solidarity across borders. 🇺🇦
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Access to Commercial Space Stations: Had a fantastic conversation with Jonathan Volk, CEO of Starlab, about the future of Commercial Destinations in Low Earth Orbit (CLD) and why the next decade of medical breakthroughs will be driven by space. In our own research on @SpaceX CRS‑16 RRRM‑1, we found that exposure to space can trigger genomic plasticity — activating pro‑angiogenic and stress‑resilience pathways that remain dormant on Earth. As CLDs like #Starlab come online, researchers will have routine access to microgravity platforms — enabling discoveries in regenerative medicine, aging biology, immunology, and tissue repair that are impossible to replicate on Earth. Space isn’t just a frontier for exploration. It’s becoming a frontier for human health. #Space #Biotech #Healthcare #ISS #CLD #Microgravity #Starlab
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Today with Governor Shapiro and Chris Mason of Cornell at the McGowan conference room celebrating the Trivedi Institute!
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Launching of Trivedi Institute of Space and Global Biomedicine! left, Dr Kate Rubins NASA astronaut now at Pitt Director of Trivedi! Next, Dr Afshin Beheshti ex-NASA now director of the space program at McGowan. Right, Dr Sylvain Costes, ex-chief data scientist, NASA now at Pitt!
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Ashok Trivedi who endowed the Trivedi Institute of Space and Global Biomedicine! A wonderful friend, and resident of Pittsburgh! Thanks Ashok!
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Tissue Reprogramming: Rewriting Medicine? Imagine your body as a massive, bustling factory where trillions of tiny workers—your cells—each have a super-specific job: peripheral nerves giving us sensation, pancreas generating insulin like pros, or skin cells scrambling to seal a wound. But when injury, disease, or aging strikes, these workers falter, leading to neuropathy, diabetes, or stubborn chronic wounds. What if we could instantly retrain the survivors right on the spot to heroically take over? That's the game-changing power of in vivo tissue reprogramming—rewiring cells' identities inside your body, no lab needed! sciencedirect.com/science/articl… This isn't sci-fi; it's cutting-edge science. Enter Tissue NanoTransfection (TNT), a breakthrough our team pioneered, first unveiled in Nature Nanotechnology in 2017 and now supported by 20+ high-impact publications. Picture a tiny silicon chip—like a high-tech sticker—placed on your skin for seconds. Zap! Safe electric pulses open nano-channels, delivering DNA or RNA to reprogram cells. Skin cells transform into blood vessels for faster healing or neurons to combat neuropathies. It's like upgrading your body's software to unlock hidden healing superpowers! How? Here is one example. Cells follow an "epigenome"—DNA's instruction manual. TNT tweaks it with precision. In the skin, a sub-family of fibroblasts naturally rewind and adapt; TNT supercharges this with targeted signals, turning these cells to express vascular properties. Vasculogenic fibroblasts appear and help bring blood supply to starving tissue. The potential? Animal studies are stunning. Human ex vivo studies are promising. Field-ready, no immune suppressants—just your body's natural defenses at work. Risks like unintended changes exist, so safety testing in humans is key. TNT zaps cells to self-heal, backed by over a decade of research. Human trials are on the horizon—imagine fixing tissues like app updates! What do you think—could this revolutionize regenerative medicine? Share your thoughts below! hashtag#RegenerativeMedicine hashtag#Nanotechnology hashtag#WoundHealing hashtag#Innovation hashtag#HealthTech
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Unveiling the Invisible Wound: When the Skin’s Silent Failures Threaten Whole‑Body Health!
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Chandan K Sen
Chandan K Sen@ChandanKSen·
Born out of PittMcGowan, Trivedi Institute and McGowan will share the same building and floor on Technology Drive! Superstar Directors of Trivedi will take our science to space! Stay tuned! Big thanks to my dear friend Ashok Trivedi for this wonderful gift to humanity! Cheers!
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Chandan K Sen
Chandan K Sen@ChandanKSen·
After Grand Round today at Miami Surgery! Very impressive dept!
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