ChemBioNAC

Proximity-Induced Ligation of Noncomplementary Oligonucleotides Triggered by Charge-Transfer Interactions by Francois Morvan, Michael Smietana, and co-workers (@Smietana_M) #OpenAccess …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ce…

When the Position of Pendant Groups Makes the Difference in G-Quadruplex Behavior: The Case of Bis-Conjugated Thrombin-Binding Aptamers #Aptamers pubs.acs.org/doi/10.1021/ac… @Smietana_M @ChemBioNAC @orozco_lab @DanielaMontesa9 @umontpellier @IRBBarcelona #JCIM Vol66 Issue1 #compchem

📢DNA templates are no longer required for efficient nucleic acid ligation. 💡We introduce Charge-Transfer Assisted Ligation (CTAL): a new templated reactivity based on π-stacking donor–acceptor interactions (DAN/NDI), not base pairing. 📄 Open access: …mistry-europe.onlinelibrary.wiley.com/doi/epdf/10.10…

@ChemBioNAC @CNRSchimie Merci à @CNRSchimie, @umontpellier de m’avoir offert un super environnement pour exercer 40 ans de recherche dont 36 exercées au @CNRS qui ont abouti à une carrière dont je suis fière. Un grand merci à mes étudiants, ingénieurs qui ont largement contribué à ma réussite.

@ChemBioNAC @CNRSchimie Mes sincères remerciements vont à l’équipe @ChembioNAC pour avoir organisé mon pot de départ entre collègues et amis. Une nouvelle page se tourne pour moi vers des activités différentes mais le flambeau des ARN modifiés et coiffés est entre de bonnes mains pour durer et réussir🤞

We were delighted to celebrate the retirement of @DebartFrancoise, closing a remarkable chapter and opening a new one. It was a warm and heartfelt moment, reflecting her dedication and the positive impact she has had on all of us over the years. Thank you Françoise! @CNRSchimie

Had a great day visiting @DebartFrancoise and Michael Smietana at IBMM in Montpellier. 😊 Thank you for the invitation, the hospitality and the scientific discussions. 🧬🤩

Our lastest article has just been released (Org. Biomol. Chem): Synthesis, duplex-forming properties, and enzymatic resistance of oligonucleotides containing N-acylsulfonamide linkages pubs.rsc.org/en/content/art… @CNRSchimie @umontpellier @enscmchimiemtp @ChemBioNAC @IBMM_Balard

🎇Please meet our next 10th Euroboron invited speaker - Michael Smietana🎇 Michael is Professor at the University of Montpellier, France. His current research focuses on molecular recognition and nucleic acid bioconjugates, in particular boron-modified nucleic acids.

Very pleased to share our latest publication on the Synthesis and Base-Pairing Properties of Oligonucleotides Containing 5′-(R)- and 5′-(S)-C-Aryl-thymidine now in JOC pubs.acs.org/doi/10.1021/ac… @DebartFrancoise @VasseurJeanJacq @HausdorffMarcel @CNRSchimie @umontpellier @ChemBioNAC

We have developed an entirely new mechanism of action for gene knockdown -> trafficking of targeted mRNAs to the lysosomal, using lysosomal trafficking oligonucleotides (LyTONs)! Published in @ChemicalScience Led by @disha_kashyap_, with @milnetom68 pubs.rsc.org/en/content/art…

Kudos to @PastorelZachary and Juliette Zanzi Great Team work with @OBasle @CanacYves @arseniyadis @elisejdumont and Alessio Bartocci @CNRS @umontpellier @IBMM_Balard @ChemBioNAC @LCC_CNRS @NiceChemistry

🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM invites applications for 2 CNRS tenure-track positions. -> Glycochemistry -> RNA Chemistry contact : du-ibmm@umontpellier.fr To apply : carrieres.cnrs.fr/recrutement-po…

Very happy to share out new pre-print on the enzymatic GalNAc-labelling of oligonucleotides. Big congrats to undergraduate student Elisa and graduate student @pierrenicolas_b ! chemrxiv.org/engage/chemrxi… @institutpasteur @CNRSchimie

🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM Balard invites applications for two CNRS tenure-track positions. -> Glycochemistry -> RNA Chemistry Contact : pascal.dumy@umontpellier.fr

Very special scientific day on the occasion of @VasseurJeanJacq retirement. Thanks to the speakers for their great lectures and thanks to all the participants. Happy retirement Jean-Jacques !🌴☀️🚴 @umontpellier @ChemBioNAC @IBMM_Balard @Philippe_Auge @PascalDumy

Fantastic lectures on photo-biocatalysis, transition-metal catalysis and organocatalysis at @UNamur chemistry department. Great dissussions with @GrimaudLaurence (ENS Paris), @Smietana_M (Univ Montpellier @ChemBioNAC), E McGarrigle (@McGarrigleGroup, UCDublin) and @OlivierRiant.

Mini-symposium this Friday at the chemistry department of @UNamur. Three invited speakers: Prof. Smietana (@Smietana_M), Grimaud (@GrimaudLaurence) and McGarrigle (@McGarrigleGroup). Looking forward to welcome you and talk about chemistry!

#EurJOC Recent Development of DNA-based Biohybrid Systems Driven by Light (Michael Smietana and co-workers) @Smietana_M @OBasle @Chembionac • onlinelibrary.wiley.com/doi/10.1002/ej…

Recent Development of DNA‐based Biohybrid Systems Driven by Light 👉…mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ej… @OBasle @CanacYves @PastorelZachary @ChemBioNAC @umontpellier @IBMM_Balard