Christopher Gayle

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Christopher Gayle

Christopher Gayle

@ChrisGizzada

Building technical resilience in the Caribbean via @thegizzada. Try our business platform @phoroscloud, designed for companies of all shapes & sizes.

Katılım Nisan 2012
469 Takip Edilen908 Takipçiler
Christopher Gayle retweetledi
Colton Ortolf
Colton Ortolf@ColtonOrtolf·
AI in healthcare isn't a product. It's infrastructure. Diagnostic tools will assume AI assistance. Treatment protocols will embed predictive models. Patient workflows will route through AI layers by default. The entire healthcare stack is shifting to AI-first architecture.
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Gregory Moore
Gregory Moore@str8gamesja·
Testing out and programming our new line of service robots
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Gordon Swaby
Gordon Swaby@Gordonswaby·
Congratulations to @mannishwaata on his newest venture (1 year later). If you’re traveling on highway 2000 out of Kingston it’s on your right; take the exit to get there. It’s in old harbor. #YodOn
Gordon Swaby tweet mediaGordon Swaby tweet media
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Dan Shipper 📧
Dan Shipper 📧@danshipper·
new model for engineering team structure in 2026: 2 people only one pirate and one architect the pirate's job is to move as fast as possible to develop valuable, shipped product features by vibe coding. the architect's job is to turn the product surface discovered by the pirate into a reliable, structured machine—also by vibe coding, but at a slower, more well-reasoned pace. every product needs a pirate but most product's only need an architect once they some form of PMF, and in that case they usually don't need one full-time. architects can work across many codebases and solve interesting technical challenges. pirates go hard on a product that they own end-to-end.
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Jamaica Observer
Jamaica Observer@JamaicaObserver·
At 32 years old, Gabrielle Gilpin-Hudson has shattered a 60-year record to become the youngest president in the history of the Realtors Association of Jamaica (RAJ). Born in 1993, Gilpin-Hudson belongs to a generation often associated with speed and disruption. Measured, thoughtful, and grounded, she brings a steady hand to an industry that has been embracing transformation. jamaicaobserver.com/2026/03/16/fro…
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Satya Nadella
Satya Nadella@satyanadella·
We’ve trained a multimodal AI model to turn routine pathology slides into spatial proteomics, with the potential to reduce time and cost while expanding access to cancer care.
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Christopher Gayle
Christopher Gayle@ChrisGizzada·
Always advocating for more unity amongst Jamaican entrepreneurs. We could take on the world together vs battling over the island’s pie. I know it’s a nice pie, but imagine what we could do.
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Runkus - A BELIEVER
Runkus - A BELIEVER@Runkusinno·
chat, we still a shout LIFE OVER DEATH?!
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Andrej Karpathy
Andrej Karpathy@karpathy·
Expectation: the age of the IDE is over Reality: we’re going to need a bigger IDE (imo). It just looks very different because humans now move upwards and program at a higher level - the basic unit of interest is not one file but one agent. It’s still programming.
Andrej Karpathy@karpathy

@nummanali tmux grids are awesome, but i feel a need to have a proper "agent command center" IDE for teams of them, which I could maximize per monitor. E.g. I want to see/hide toggle them, see if any are idle, pop open related tools (e.g. terminal), stats (usage), etc.

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Teng Yan
Teng Yan@tengyanAI·
The most important sentence in Karpathy's whole post is probably this: anything with a measurable score and fast feedback will become something agents can optimize for you. automatically with no humans involved.
Andrej Karpathy@karpathy

Three days ago I left autoresearch tuning nanochat for ~2 days on depth=12 model. It found ~20 changes that improved the validation loss. I tested these changes yesterday and all of them were additive and transferred to larger (depth=24) models. Stacking up all of these changes, today I measured that the leaderboard's "Time to GPT-2" drops from 2.02 hours to 1.80 hours (~11% improvement), this will be the new leaderboard entry. So yes, these are real improvements and they make an actual difference. I am mildly surprised that my very first naive attempt already worked this well on top of what I thought was already a fairly manually well-tuned project. This is a first for me because I am very used to doing the iterative optimization of neural network training manually. You come up with ideas, you implement them, you check if they work (better validation loss), you come up with new ideas based on that, you read some papers for inspiration, etc etc. This is the bread and butter of what I do daily for 2 decades. Seeing the agent do this entire workflow end-to-end and all by itself as it worked through approx. 700 changes autonomously is wild. It really looked at the sequence of results of experiments and used that to plan the next ones. It's not novel, ground-breaking "research" (yet), but all the adjustments are "real", I didn't find them manually previously, and they stack up and actually improved nanochat. Among the bigger things e.g.: - It noticed an oversight that my parameterless QKnorm didn't have a scaler multiplier attached, so my attention was too diffuse. The agent found multipliers to sharpen it, pointing to future work. - It found that the Value Embeddings really like regularization and I wasn't applying any (oops). - It found that my banded attention was too conservative (i forgot to tune it). - It found that AdamW betas were all messed up. - It tuned the weight decay schedule. - It tuned the network initialization. This is on top of all the tuning I've already done over a good amount of time. The exact commit is here, from this "round 1" of autoresearch. I am going to kick off "round 2", and in parallel I am looking at how multiple agents can collaborate to unlock parallelism. github.com/karpathy/nanoc… All LLM frontier labs will do this. It's the final boss battle. It's a lot more complex at scale of course - you don't just have a single train. py file to tune. But doing it is "just engineering" and it's going to work. You spin up a swarm of agents, you have them collaborate to tune smaller models, you promote the most promising ideas to increasingly larger scales, and humans (optionally) contribute on the edges. And more generally, *any* metric you care about that is reasonably efficient to evaluate (or that has more efficient proxy metrics such as training a smaller network) can be autoresearched by an agent swarm. It's worth thinking about whether your problem falls into this bucket too.

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Peter H. Diamandis, MD
Peter H. Diamandis, MD@PeterDiamandis·
OpenAI ran 86,000 experiments in 2 days. AI is talking to robotic labs in a tight loop. Result: a protein synthesized at 40% lower cost. This is the new scientific method.
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Philip Rosedale
Philip Rosedale@philiprosedale·
This is so beautiful. And so important to study. This phenomena (emergent coherence) is central to much of life, and most people don't even imagine it could happen.
Interesting STEM@InterestingSTEM

They capture the exact moment when a developing heart shifts from silence to its first beat. There is no “switch”: many cells gradually become active and, upon crossing a critical threshold, the entire tissue suddenly synchronizes.

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