Circulation

Most patients on dofetilide paid more with insurance than a transparent generic option ($12.36/month), with median savings ~$28/month, highlighting that insurance does not always translate into lower costs @andresenriqueza @Dr_Nazarian_EP @Dr_Markman ahajrnls.org/4rH40oY

High-dose flu vaccines may modestly reduce cardio-respiratory and HF hospitalizations in older adults, but not MI, stroke, or CV death. Benefits likely reflect preventing infection-related decompensation and support flu vaccination as part of CV care.ahajrnls.org/4lP2oIr

Recent trials suggest that digitalis may benefit selected symptomatic #HFrEF patients, but modest effects, safety, and fragility warrant caution @shaan_khurshid @DrCardioCon @GivertzMichael ahajrnls.org/47emhCF

This afternoon! Come over to Independence East to grab some refreshments and meet Editors (and Editors-Elect) of @CircAHA and @CircOutcomes #EPILifestyle26

Don't miss the Editor's Note introducing the @CircOutcomes special issue from @KBreathettMD @NorrinaA @emilycob Designing for Action: Advancing Epidemiology to Improve Cardiovascular Health ahajournals.org/doi/10.1161/CI… @AHAScience

🚨JUST PUBLISHED 🚨@CircOutcomes focus issue on #CardiovascularEpidemiology led by @KBreathettMD @NorrinaA @emilycob Epidemiology is at an inflection point where we must move from description toward action-oriented science 📖 Read here: ahajournals.org/toc/circpopout… @bnallamo

Attending #EPILifestyle26? Join American Heart Association Journal Editors, including @CircAHA EIC-Elect Dr. Bradley Maron, to learn more about publishing in the journals. 🗓️TOMORROW, March 18 🕔5-6pm ET 🎯 Independence Ballroom East

Co-published by @ACPinternists and @AHAScience #AHAJournals, @AnnalsofIMCC is a peer-reviewed, open access journal that publishes #casereports, case series, and image/video cases across the spectrum of medicine. Learn more and submit to AIMCC today at ahajrnls.org/3GBOSW0

@DrJESalem @JuanQinMed @AmirZMunir @CardioOncology

CXCR6+ T-cells drive ICI Myocarditis ahajrnls.org/4r0RQrk

GRSF1 Balances BCAAs to Prevent Heart Failure ahajrnls.org/3LaMw5j

@neallakdawala @drjamesware @CrottiLia @tikuowens @AdamHelmsMD @jodieingles27 @IacopoOlivotto : @sday_hcm @ulvedreng

Non-sarcomeric HCM is associated with hypertension and obesity, needing blood pressure weight management, whereas sarcomeric HCM carries a more adverse prognosis, necessitating intensified monitoring for arrhythmias and systolic dysfunction.ahajrnls.org/4sDK0EA

@MichaelJBlaha @ZeinaDardari @CiccaroneCenter @FSPH_IU @FraminghamStudy : @EmeliaBenjamin @dramitkhera @MBittencourtMD @PauloLotufo @KunalJhaMD @DebbieCohenMD @ya

Obesity phenotypes and cardiovascular disease ahajrnls.org/4ruMCVl

@AmmiratiEnrico @ospniguarda @jakreally @FormazioneHPG23

Parvovirus B19-associated myocarditis in children ahajrnls.org/450fT0P

PRMT3-mediated arginine methylation stabilizes PCSK9 and promote aortic valve calcification. Selective inhibition of PRMT3 can be a new non-invasive therapeutic strategy to slow or prevent progression of calcific aortic valve disease.ahajrnls.org/413uplW

Transition of cardiac fibroblasts to myofibroblasts in the right ventricle (RV) is a key driver of RV failure. RV myofibroblast mitochondrial UCP2 loss-of-function SNPs or inflammatory cytokine TNFa are potential biomarkers for early RV decompensation i....ahajrnls.org/4bk3hnp

TRIM28 protects the heart from ischemia/reperfusion injury by ubiquitinating IRP2 and suppressing ferroptosis. ahajrnls.org/4lsqXuB