Cksl18

Look at this beauty 😍 The architecture of a postnatal lung (accessory lobe) as shown by a-SMA staining of the airway smooth muscle cells 🫁 #FluorescenceFriday

@hanbitbaek @iscience ❤️

I am so excited to share that my best friend @Cksl181 has published her thesis work on how Truncated NTRK2 is induced in CAP1 endothelial cells during mouse lung injury-repair @iScience! Please go check it out!!! 🥳 cell.com/iscience/fullt…

Lung diseases in one page

It’s a dopamine world and we live in it.

1/10 Excited to share our latest - the first whole-body map of both DNA methylation and 3D genome at single-cell resolution.

🚨 BREAKING: With @NIH cuts leaving young researchers in limbo, CRI is stepping up - $2.5M for postdocs to keep #CancerResearch moving forward. Breakthroughs tomorrow depend on investing in young scientists today. Read more: bit.ly/4iEQNsJ #FundingScience

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon hubs.li/Q037Z0gv0 Open stem cell research from @CellStemCell

Why arthritis pain persist after inflammation resolves? Our study in @PNASNews shows that impaired macrophage resolution in DRG sustains pain via proinflammatory lipid imbalance. Targeting this pathway may offer pain relief! Congrats @SilviaOggero & team! pnas.org/doi/10.1073/pn…

Transitional cell states sculpt tissue topology during lung regeneration @LeaElHaddad, @arvikonk, @Tatalab_Duke, @KonishiSatoshi, @TataAleksandra hubs.li/Q037Z6nT0 Open stem cell research from Cell Stem Cell.

Online Now: Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma dlvr.it/TJP2rr

iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immune microenvironment dlvr.it/TJP2QP

Decoding aging-dependent regenerative decline across tissues at single-cell resolution hubs.li/Q037Z3bS0 Open stem cell research from Cell Stem Cell.

Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation dlvr.it/TJP2lt

Online Now! Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature dlvr.it/TJKM8L #stemcells

I’m excited to share my work over the last few years with @JD_Buenrostro! Chronic inflammation creates an epigenetic memory in colonic stem cells, priming them for tumor growth: tinyurl.com/ColitisNagaraj…. Here’s a walkthrough of what we found (🧵)

My personal website is now up! I plan to post detailed lab protocols for CRISPR gene editing, tissue sectioning, and immunostaining. Check it out at nicoleedwardsphd.com

Proud to share our latest work in partnership with Dr. Ke Yuan presenting a novel animal model to study pericytes in vivo: embopress.org/doi/full/10.10…

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease Jennifer Dickens, @LabRawlins and collaborators embopress.org/doi/full/10.10…

Terren and Joe are off to a great start in the New Year with their new opus tracking lung regeneration over a year post flu (strong assist from Mike Morley!). Endothelial cells don't fully recover! this was a fun trip and #WhyWeScience! cell.com/cell-stem-cell…

Epigenetic regulation of placental vascularization – now published in @Dev_Cell (sciencedirect.com/science/articl…). Congratulations and thanks to @StephGehrs for fantastic work and paving the way of the augustinlab.de into the world of vascular epigenetics. There’s more to come!

Huge congratulations to my best friend, @hanbitbaek, on the publication of her beautiful scientific work focused on ERK signaling in maturing oocytes in C. elegans. A true tour de force 🙌⭐️🏆 ⁦@CellReports⁩ Please go check it out! cell.com/cell-reports/f…