Claire Prince

V excited to share our latest paper which explores #Mendelianrandomisation (MR) methods used to perform #lifecourse research and #systematically reviews work that has utilised MR to elucidate effects of factors acting at different stages of the lifecourse: tinyurl.com/yck6kb35

Investigation into the causal genetic association between adiposity and reproductive factors. Read the full study by @Claire_Prince_, @laurahowe_epi, @abifraser1, @BeckyRichmond90. and Gemma C Sharp here: bmcmedicine.biomedcentral.com/articles/10.11…

Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes @AJHGNews article @GeneticsSociety @Claire_Prince_ @iTomRichardson hubs.li/Q01L6xt60

Excited to share our preprint which uses multivariable mendelian randomization methods to untangle the relationships between adiposity and reproductive factors @BeckyRichmond90 @abifraser1 @laurahowe_epi

Excited to share my paper investigating relationships between women’s reproductive factors using Mendelian randomization! Check it out here: rdcu.be/cJG0z @BeckyRichmond90 @ammegandchips @laurahowe_epi @abifraser1

Take a look at our paper where we explore the effects of genetically predicted gene expression on 14 immune-associated and cancer outcomes. With @iTomRichardson and @drrmitch cell.com/ajhg/fulltext/…

Happy to share the preprint where we use Mendelian randomization methods to elucidate causal links between reproductive factors in women @BeckyRichmond90 @ammegandchips @abifraser1 @laurahowe_epi medrxiv.org/content/10.110…

Excited to share our paper investigating the epigenetics of e-cigarette use doi.org/10.1186/s13148…

As part of SEE-Cigs (Studying the Epigenetics of E-cigarettes), we recruited e-cigarette users who reported having a limited smoking history and used DNA methylation to: 1) verify their non-smoking status and 2) assess the biological impact of e-cigarettes distinct from smoking

Excited to share the preprint of work with @iTomRichardson and @drrmitch which explored immune-cell regulatory mechanisms and genetic architecture of 16 autoimmune and cancer outcomes using multi-omics methods