Connor Murphy 🌁

Every VC knows this pain. A founder starts a raise… and the spreadsheet lands. “Warm intro tracker_v7_FINAL.” We’re testing a new way to fix it, Raise (by @brdgapp ). A reusable, founder-friendly way to offer intros without the chaos. No more spreadsheets. No duplicate effort. DM for early access.

Agentic development = coaching claude on how to better think about problems

@FinnMurphy12 Check out meta-flux.com as nailing this

90% of clinical trials fail and it’s not for a lack of trying. We spend over a quarter trillion a year to solve the ailments that trouble you and your loved ones. But we haven’t figured out how to convert that spend into an improving hit rate in finding the drugs that change lives. So today a 28 year old with eczema has two choices: a steroid cream that wrecks her skin with long-term use, or a $37,000/year injection that only has a 50/50 chance of success. @viswacolluru looked at those numbers and figured there must be a better approach. The most successful drugs in history have come from nature. Aspirin, taken by 1 in 3 Americans daily, is from willow bark. Metformin, used by 500 million diabetics, is from a plant, Goat's Rue. Quinine from tree bark was first added to tonic water to mitigate malaria in pasty Europeans in the tropics. Half of all FDA-approved drugs are sourced from the natural world. So Viswa created Enveda to unlock the 99% of nature's chemistry that we haven’t been able to read until very recently, and went from seed to unicorn in 5 years doing it. It was really special to sit down with both Viswa and @pablolubroth at @lifeschemistry’s Boulder HQ for the Season 1 finale of Forecast 2050 to talk about the future of medicine. We discuss: - Why capital markets have been bad for patients. - Why insisting on understanding how drugs work in the body is actually slowing down drug discovery. - Why aging is not inevitable, and how to stop your body from killing you. - Why mental health will be the defining medical crisis of the next 25 years as the mindsugar of TikTok AI slop only gets more corrosive. youtu.be/C5mSD1eY7J0 Show Notes & Transcript in the comments👇

SF vibes - while adding 40,000 students in the last week. Breaking our $7,000+ a day and closing schools in 3 countries. Let's go

The biggest opportunity for would-be startup founders is AI. But the most underpriced opportunity is probably non-AI ideas. So if you have a good non-AI idea, go for it, because everyone else is going to overlook it.

@1250 @phillip_mckenna We are still pre ipo

@phillip_mckenna Surprised you haven't upgraded yourself to Business Class yet 😆

Just hit 1 Million Students on SimpleStudy. Now off to San Francisco 🌉🚀 Don't do consumer ;)

@deckelly @rod_mallo Inverted fomo

@rod_mallo you do love your hard truths

if you come across this founder, don't believe a word he says

I've joined @usv

If your ancestors lived in Ireland in the 1800s, you are 9 times more likely to live in the USA than Ireland.

.@newtgingrich and I were delighted to attend a St. Patrick’s Day celebration hosted by Ambassador Aoife McGarry and Mr. Connor Murphy from Ireland.🍀

Ambassador Callista L. Gingrich and Speaker Newt Gingrich were delighted to attend a St. Patrick’s Day celebration hosted by Ambassador Aoife McGarry and Mr. Connor Murphy from Ireland.🍀

The fertiliser crisis - 40% of urea processed from gas in the gulf. Meant to be used by farmers this quarter. Crop yields will be a lot lower this year. Good pod on the 2nd order impacts of the war podcasts.apple.com/ie/podcast/odd…

@FinnMurphy12 @tylercowen It must be a sign of "deep thinking mode" for humans :)

@ConnorPM @tylercowen we did not co-ordinate the jumpers - but they are cosy

Hi AI - can you merge the intelligence and infectious curiosity of @tylercowen with the optimism and risk appetite of @FinnMurphy12 - maybe throw in some cups of teas and wooly jumpers for the craic :) Looking forward to listening to this in full

100 percent

21% in Ireland

@jefielding The teams do that “bit” :) I.e. the team picks the thesis, market… We just pick the teams

@ConnorPM True. But building bits or atoms?

Half the VCs I know are changing their focus areas / investment thesis right now. Feels like a moment of deep reflection - or panic.