Corey Giles

Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease. disq.us/t/488pjoj Pheweb at metabolomics.baker.edu.au

📢ACDC is a platform for discovery & validation of #CVD mechanisms, biomarkers & predictive risk models. It brings together almost 400,000 individuals from Aust clinical & population cohorts, many of which have molecular profiling @OzCvA

New online! Building the Australian Cardiovascular disease Data Commons nature.com/articles/s4156…

Depression often co-occurs with chronic illness, e.g. heart disease, diabetes and obesity, which may be explained by chronic inflammation & metabolic dysfunction. But, what is the course of immunometabolic dysfunction in depression and how that may relate to brain changes?🧵1/6

Not only will you be working with industry leading AI scientists, you will be working on Australia's newest Cardiovascular disease resource: The Australian Cardiovascular disease Data Commons (ACDC) - bringing together approximately 400,000 individuals from 18 cohorts nationwide.

PhD Scholarship opportunity! Funded by the Australian Centre for Artificial Intelligence in Medical Innovation (ACAMI), we have a PhD scholarship to Accelerate Cardiovascular Disease Risk Prediction with Artificial Intelligence. latrobe.edu.au/study/scholars…

🎉 Congrats to @CoreySGiles, winner of the 2024 Baker Symposium John Funder Award for best presentation by an #ECS in discovery #research for his multi-ancestry lipidomic genome-wide association study that revealed novel genetic drivers of lipid metabolism & links to disease.

👏 to @CoreySGiles, who spoke about how he's using #AI in his #lipidomics work at yesterday's #AlfredResearchWeek AI in #science panel hosted by @DrShaneRRR . Very cool #research coming out of @Alfred_Research. #heartdisease #risk. @PeterJMeikle

Our latest publication in @JACCJournals introduces a novel blood-based lipidomic risk score for heart disease. doi.org/10.1016/j.jacc…

📣 @PeterJMeikle paper finds lipidomic-based metabolic age is associated with ⬆️ risk of #CVD, #diabetes & all-cause mortality, independent of chronological age. mAge score has potential to identify those at ⬆️ risk of #metabolicdiseases. thelancet.com/journals/ebiom… @OzCvA @latrobe

Our study across ~15,000 participants shows strong links between the Pls Score and lower risks of type 2 diabetes, heart disease, and mortality. In a placebo controlled trial, we show it responds to dietary supplementation!

Exciting news from our latest research! We've developed a plasmalogen score (Pls Score), a new biomarker that could change how we assess metabolic health. authors.elsevier.com/sd/article/S23… @BedimoBeyene @BakerResearchAu

Our SBayesRC method is now published in Nature Genetics! SBayesRC is a full Bayesian method for polygenic score prediction that can analyse all common variants jointly with functional annotations in a single step. @zhili_zheng @IMBatUQ nature.com/articles/s4158…

Lipidomics, the study of fats in the body, is a key area of focus for us. This is a rapidly growing field of science and a critical one because lipids play a big part in regulating our #metabolism and our risk of disease. Here's a brief insight into our #lipidomics work.

New paper from the @BakerResearchAu Metabolomics Lab. Imputation of lipid species to facilitate integration of lipidomic datasets rdcu.be/dzawU Congrats Aleks!

An @nhmrc Investigator Grant will build on our exciting #lipidomics work. Delighted to share that @CoreySGiles from our Metabolomics lab has received a grant to decipher genetic drivers of lipid dysregulation in cardiometabolic diseases. Congrats Corey! baker.edu.au/news/media-rel…

@BakerResearchAu @Dr_YKTham Some more awesome people from the lab: @ArachidonicAlex @AlexFaulkner44 @AaronJurrjens @BedimoBeyene @KevinHuynhTweet @MichelleCinel @PeterJMeikle @DrSatvika @sudip_bcmb @ThomasGMeikle @Tingtin49606292 @yi_changyu @YSchooneveldt

HELP ALERT 📣 Help us name our #Metabolomics team’s newest #MassSpec after an inspiring historical female #scientist. Choose from the options below or suggest one in the comments. baker.edu.au/news/institute… @CoreySGiles @Dr_YKTham

Exciting new research published in @NatureComms! We (@BedimoBeyene, @BakerResearchAu) introduce the metabolic BMI score (mBMI) to evaluate metabolic health beyond just weight. This sheds light on the concept of “metabolically healthy obese”. rdcu.be/dn3y0

Great representation from the Metabolomics laboratory at @LipidomicsForum! It was great being able to talk about our work & also see some really interesting research in the lipid space. @BakerResearchAu @SABE_latrobe

frontiersin.org/articles/10.33… My latest work in human milk lipidomics. Does a lack of exposure to unique human milk lipids contribute to increased disease risk? A huge effort from a huge team, >600 human milk samples & ~1000 lipid species #lipidomics #breastfeeding #DOHaD