COSMIC CryoEM

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COSMIC CryoEM

COSMIC CryoEM

@CosmicCryoEM

A freely available web platform for protein structure prediction and #cryoEM data analysis via #cloudcomputing at @SDSC_UCSD (Tweets mostly by @mcianfro)

San Diego, CA Katılım Mayıs 2016
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
🚨Updates🚨 We have two updates to share: 1) We have updated #AlphaFold and #ColabFold to the latest version (v2.3.1) and 2) we added #ESMFold as a new structure prediction tool. Let us know how it goes for you! See thread ->
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
🚨Updated tool alert🚨 We have updated #modelangelo to v1.0.1. See thread below about changes - updates include working beautifully for protein, DNA, and RNA😍. Ex: PDB 8G1I / EMDB 29671 that has protein, dsDNA, and RNA twitter.com/SjorsScheres/s…
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
2) We added a new structure prediction tool: #ESMFold. #ESMFold utilizes protein sequence alone (no multiple sequence alignments) for structure prediction. It is ~5-10X faster than AlphaFold and offers a different approach for structure prediction. cosmic-cryoem.org/tools/esmfold/
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
1) Thew newly updated #AlphaFold2 and #ColabFold are faster and can predict up to 5500 amino acids (!!). NOTE: We merged all AlphaFold tools together so you'll find Multimer within the AlphaFold2 task
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
🚨Updates🚨 We have two updates to share: 1) We have updated #AlphaFold and #ColabFold to the latest version (v2.3.1) and 2) we added #ESMFold as a new structure prediction tool. Let us know how it goes for you! See thread ->
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COSMIC CryoEM retweetledi
Michael Cianfrocco
Michael Cianfrocco@mcianfro·
Here, I'll talk about how we use @globus for data transfer into @CosmicCryoEM and using @globus for moving data in/out of @awscloud for our @UMLifeSciences #cryoEM workshop
AWS Education@AWS_Edu

Data management is becoming increasingly complex. Join us for expert tips on how to address these challenges & hear from @mcianfro on how @globus—together with AWS—helps him manage the massive amounts of research data generated by microscopes. go.aws/3D4de9k

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Michael Cianfrocco
Michael Cianfrocco@mcianfro·
👇 An old script from grad school that uses SPIDER to align averages with a 3D volume. A tried and true script that confirms my 3D maps match class averages. Essential for my PhD work mapping conformational changes in TFIID pubmed.ncbi.nlm.nih.gov/23332750/
COSMIC CryoEM@CosmicCryoEM

🚨New tool alert🚨 Ever wanted to compare a 3D reconstruction or a PDB with #cryoEM 2D class averages? We added a tool that will find the best matching projections of an MRC or PDB with 2D averages. cosmic-cryoem.org/tools/alignpro…

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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
This is a great way to check if an #AlphaFold prediction matches your 2D averages. OR confirming that your 2D averages match your ab initio or 3D refined maps 💅
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COSMIC CryoEM
COSMIC CryoEM@CosmicCryoEM·
🚨New tool alert🚨 Ever wanted to compare a 3D reconstruction or a PDB with #cryoEM 2D class averages? We added a tool that will find the best matching projections of an MRC or PDB with 2D averages. cosmic-cryoem.org/tools/alignpro…
COSMIC CryoEM tweet media
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Edward T Eng
Edward T Eng@edward_eng·
Early registration deadline for @ACAxtal #aca2022 is May 31st. Want to receive hands-on training with #cryoEM sample preparation instrumentation? Sign up for WK-5: CryoEM sample preparation training held at @CryoEM_PNCC during workshop Friday 7/29/2022. amcac.memberclicks.net/aca-wk5
Edward T Eng tweet media
ACAxtal@ACAxtal

Early registration for #acameeting2022 #acamtg2022 #aca2022meeting #Portland ends in one week! Register today to save! #crystallography #structuralscience #cryoem #sciencetwitter #chemistry #diffraction #Biology #xrd #bio acameeting.com

Portland, OR 🇺🇸 English
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@DTegunov @cianfrocco_lab @SjorsScheres @globus @awscloud @UMLifeSciences @jeffreyjgray @ACAxtal