David M. Sabatini

We are thrilled to announce the 13 winners of the 2026 Pershing Square Sohn Cancer Prize. Doubling our commitment, this year's scientists have been selected for their bold ideas and potential to transform cancer research. Please join us in congratulating: pershingsquarephilanthropies.org/news/pershing-…

New out this week from our lab in @NatMetabolism. We measured dynamic aspartate changes following mitochondrial inhibition, finding that SDH inhibition causes a counterintuitive rebound effect mediated by succinate impairing pyrimidine synthesis. nature.com/articles/s4225…

The franchise continues in 2026. 67 years on the market and we still wonder how metformin works. Congrats to Nav and team nature.com/articles/s4225…

Someone having fun with mTOR antibody labelling

Thank you Dr. Navdeep Chandel from @NUFeinbergMed for visiting us, for a fantastic lecture on mitochondrial biology and signaling, and for a very exciting and stimulating conversation as part of this month’s Cutter Distinguished Lecture series 🧿🧿

Very honored to have received the J. Heyrovsky Memorial Medal for achievements in chemical sciences from the President of the Czech Academy of Sciences. I am grateful to all group members and collaborators for their contributions! @IOCBPrague avcr.cz/cs/udalosti/AV…

Huge congrats to my postdoc mentor Ralph DeBerardinis on his election to NAS!! 🥳🥳🥳 An inspiring physician-scientist and wonderful person and mentor.

Warmest congratulations to the newly elected members of the United States National Academy of Sciences. nasonline.org/news/2026-nas-…  This is an extraordinary honor recognizing profound contributions to science and society. I am especially delighted to celebrate my colleagues elected to the Section 41: Drs. @AttardiLaura, @RJDLab, Benjamin L. Ebert and Michael Stratton. Your groundbreaking work continues to shape the frontiers of discovery and inspire the next generation. A truly remarkable achievement,…Bravo! @Stanford, @DanaFarber (x.com/DanaFarber), @UTSWMedCenter, @NorthwesternU, @NUFeinbergMed, @theNASEM, and @theNASciences, @CellCellPress, @Nature, @ScienceMagazine

Our paper on NIH reform is now out. Thank you @Health_Affairs for the opportunity to publish it.

super proud of Gavin Chang for successfully presenting his Senior Honors Thesis this afternoon! after getting 2 yr of awesome training from Kyle, Gavin spent his senior year operating w/the independence of a grad student, while balancing a full course load & clinical shadowing!

🏅 Zuzana Keckesova has been named among the top ten Czech personalities and projects in this year’s Innovators of the Year survey organized by @hospodarky. See more ► uochb.cz/en/news/794📲 #IOCB #UOCHB #IOCBPrague #TaverenTherapeutics #chemistry #cancerresearch

We’re pleased to announce that Dr. Marcus D. Goncalves, a nationally recognized endocrinologist and physician–scientist, has been appointed director of the Holman Division of Endocrinology, Diabetes, and Metabolism at NYU Langone Health! Learn more: bit.ly/3Oya0mA

David Sabatini from IOCB Prague/Boston and Katerina Rohlenová from BTI Prague organize fantastic Prague Metabolism and Signaling Symposium (Karen Vousden, Michael N. Hall and others. Register now! praguemetabolismsymposium.com

So happy to see you join such an amazing department and university for exploring metabolism and cell biology. Can't wait to see you continue your rock star career. Congratulations!

Thrilled to share that I’ll be starting my lab as an Assistant Professor and Endowed Scholar in @UTSWMedCenter Molecular Biology Dept this Fall! 🥳 We’ll study #peroxisomes #mitochondria #metabolism via the lens of neonatology👶🏻, a very exciting frontier in medicine! #neotwitter

🧫 IOCB Prague is launching the first edition of the new international #DreamBiologyAward, a competition organised by @tomas_pluskal & @DMSabatini that offers young scientists the opportunity to present their ambitious scientific visions in the life sciences. Applications can be submitted until July 31, 2026 at ► dreambiologyaward.org/participate #DBA #biology #IOCB #IOCBPrague #visionary #vision

It has come to our attention that some people had trouble registering for the 2026 Prague Metabolism and Signaling meeting in June. So we reopened the registration portal at: praguemetabolismsymposium.com Only a few spots remain! Please RT. @katerinarohlena

Grateful to be inducted into the American Association of Physicians. Thankful to mentors/@DanaFarber colleagues/ trainees/patients who continue to teach and inspire me. Thank you @KimrynRathmell and @leonard_zon for the nomination, & to @AminNassarMD (E-Gen @the_asci awardee) for being my +1!

Honored to recieve the 2026 UCSF Byers Award in Basic Science. Eternally grateful to my mentors, colleagues and friends for your support and to all the past and present Perera Lab members to whom this honor is dedicated to 🙏🏽

Our new work by @shanshanliu1218 and @gadmark addresses a fundamental question: how does ER maintain its unique oxidizing environment, while rest of the cell is reducing? Here, we identify SLC33A1 as the major ER GSSG exporter in mammalian cells. nature.com/articles/s4155…