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Check out this video featuring @NIH_ORIP funded projects and highlighting opportunities for collab
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DRSC-BTRR & DRSC-TRiP at Harvard Med School
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DRSC-BTRR & DRSC-TRiP at Harvard Med School
@DRSC_TRiP
Account for the DRSC-BTRR (NIH P41 GM132087), current iteration of the DRSC & TRiP, a community-focused facility for fly and other insect genetic technology R&D
Boston, MA Katılım Ocak 2018
52 Takip Edilen948 Takipçiler
Big thanks to these related groups and funders & the whole #Drosophila community! @NIGMS @DrosDGRC @flystocks @FlyBaseDotOrg @alliancegenome @PerrimonLab
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Check out this video featuring @NIH_ORIP funded projects and highlighting opportunities for collab
English
DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
#DIOPT 9.1 now also includes predictions for A. gambiae (African malaria mosquito) and E. coli. (Thanks to @rmwaterhouse for doing a release tweet for us!)
@DRSC_TRiP
Rob Waterhouse also @rmwaterhouse.bsky.social@rmwaterhouse
@FlyBaseDotOrg Updated DRSC Integrative Ortholog Prediction Tool (DIOPT) to v9.1. including the following orthology prediction algorithms: Compara, eggNOG, Hieranoid, Homologene, InParanoid, OMA, OrthoDB, OrthoFinder, OrthoInspector, OrthoMCL, Panther, Phylome, SonicParanoid, and Domainoid.
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New tech: Genome-wide CRISPRa screening in fly cells!
Perrimon Lab@PerrimonLab
New paper: Xia, B., Viswanatha, R., Hu, Y., Mohr, S. E. and Perrimon, N. (2023) Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophilacells. Elife 12:e85542. doi: 10.7554/eLife.85542. PMID: 37078570
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Our newest online resource, PANGEA, and many others for #Drosophila, other genetic model organisms, mosquitos, and more can be accessed at our 'tools overview' page:
fgr.hms.harvard.edu/tools
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
New FlyBook chapter:
Visual processing in the fly, from photoreceptors to behavior academic.oup.com/genetics/artic…
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
ModERN consortium project #Drosophila
Genetics Society of America@GeneticsGSA
Fisher et al. present a global analysis of the first 45 transcription factors knockdown experiments in the ongoing modERN consortium project, along with more detailed results from individual knockdown experiments. #GENETICS| bit.ly/3OwiurR
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
Drosophila community friends - please help spread the word for nominations for the Elkins Memorial Lecture at the 2023 Cold Spring Harbor Neurobiology of Drosophila Meeting. It’s a great opportunity to support and recognize our graduate student colleagues in the field!
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If you're planning to make a KO cell line, a GLAD "Find group membership" search with your target gene can tell you if the gene is on this list--i.e., tell you if there's evidence that the KO you're trying to make is likely to result in non-viable cells
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New at our GLAD online resource, list of genes that 'dropped out' in a genome-wide CRISPR screen in S2R+, suggesting they are essential for growth and/or viability in this cell line
GLAD:
flyrnai.org/tools/glad/web/
Data source:
elifesciences.org/articles/36333
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Save the date, Boston fly folks -- the 2023 Boston Area Drosophila meeting will be June *14*!
bostonareadrosophilameeting.com
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
Calling all European fly researchers! The 2023 European Drosophila Board elections are open! Closing date is May 19th. The candidate statements and voting link are on the EDS web site: europeandrosophilasociety.org/node/15
Make your vote count! Results announced @EDRC2023
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
We've added a new graphical display for the Fly Cell Atlas single-cell RNA-Seq data, found in the “High-Throughput Expression Data” subsection of the Expression section of Gene Reports. This new graph shows how a gene is expressed across the major cell types of the adult fly.
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Excited to see use of our NanoTag technology reported in a preprint from the Gelfand lab:
Drosophila oocyte specification is maintained by the dynamic duo of microtubule polymerase Mini spindles/XMAP215 and dynein biorxiv.org/content/10.110…
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
Today's #FlyBaseTweetorial goes out to the user who wanted to know how to find a cDNA for a specific #transcript_isoform at #DROS23. We showed him the hard way to do it, and remembered the easy way a few minutes later. FlyBase user studying kayak, this is for you.
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Starting very soon (10 AM Central Time):
If you're registered for ADRC #Dros23 you can visit the app to join today's virtual CRISPR workshop with presentations on technologies and resources you won't want to miss!
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DRSC-BTRR & DRSC-TRiP at Harvard Med School retweetledi
Multiplexed Transgenic Selection and Counterselection Strategies to Expedite Genetic Manipulation Workflows Using Drosophila melanogaster …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…
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Serial Recombineering Cloning to Build Selectable and Tagged Genomic P[acman] BAC Clones for Selection Transgenesis and Functional Gene Analysis using Drosophila melanogaster …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…
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Check out this trio of #Drosophila protocols just out from Venken et al.
Synthetic Assembly DNA Cloning to Build Plasmids for Multiplexed Transgenic Selection, Counterselection or Any Other Genetic Strategies Using Drosophila melanogaster …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…
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