Dash Lab

Researchers at @iacskolkata have designed artificial membrane transporters that mimic natural membrane channels using self-assembling bis-guanosine derivatives. The stimuli-responsive, size selective nanostructures efficiently deliver drugs and dyes into cancer cells, offering new possibilities in precision therapies. Read more: doi.org/10.1016/j.xcrp… @DrJitendraSingh @rajesh_gokhale @India_Alliance @CSIR_NIScPR @SMCC_NIScPR

Prof. Jyotirmayee Dash has joined the Editorial Board of Bioorganic & Medicinal Chemistry Letters, a highly regarded journal that publishes research in bioorganic and medicinal chemistry. sciencedirect.com/journal/bioorg…

Self-assembled lipophilic guanosine derivatives modulate membrane transport across lipid bilayers: Cell Reports Physical Science cell.com/cell-reports-p…

Check out our new publication in @NatureComms 🥳 In collaboration with the lab of Dr. Jyotirmayee Dash "A non-B DNA binding peptidomimetic channel alters cellular function" Full text: nature.com/articles/s4146…

Sharing a roadmap: authors.elsevier.com/a/1j%7EUFEz97D…

Synthesis of Phenanthrenes and 1-Hydroxyphenanthrenes via Aromatization-Assisted Ring-Closing Metathesis: toward Polynuclear Aromatic Hydrocarbons | The Journal of Organic Chemistry pubs.acs.org/doi/full/10.10…

Guanosine-based hydrogel as a supramolecular scaffold for template-assisted macrocyclization - now published in Chemical Communications pubs.rsc.org/en/content/art…

Happy to Share our recent article: A non-B DNA binding peptidomimetic channel alters cellular functions Nature Communications volume 15, Article number: 5275 (2024); rdcu.be/dLtEL

Efficient Synthesis of Cyclohepta[b]indoles and Cyclohepta[b]indole‐Indoline Conjugates via RCM, Hydrogenation, and Acid‐Catalyzed Ring Expansion: A Biomimetic Approach - Parui - Chemistry – A European Journal - Wiley Online Library …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…

Combating Multidrug-Resistance in S. pneumoniae: A G-quadruplex Binding Inhibitor of Efflux Pump and its Bio-Orthogonal Assembly academic.oup.com/narmolmed/arti…

Guanosine-based hydrogel as a supramolecular scaffold for template-assisted macrocyclization - now published in Chemical Communications pubs.rsc.org/en/content/art…

Total Synthesis of Racemic Benzomalvin E, a Quinazolinone Isolated from Pencilium sp. FN070315 and Exploration to the Direct Synthesis of (E)-Benzomalvin B | The Journal of Organic Chemistry pubs.acs.org/doi/full/10.10…

Selective Recognition of c-KIT 1 G-Quadruplex by Structural Tuning of Heteroaromatic Scaffolds and Side Chains | ACS Medicinal Chemistry Letters pubs.acs.org/doi/10.1021/ac…

Potassium tert-Butoxide-Mediated Cascade Synthesis of Rutaecarpine Alkaloid Analogues: Access to Molecular Complexity on Multigram Scales | The Journal of Organic Chemistry pubs.acs.org/doi/10.1021/ac…

Pleased to share this #JOrgChem article by @DashLab1 and @SOUMYABASAK81 on KOtBu-mediated cascade synthesis of rutaecarpine alkaloid analogs from 2-aminobenzonitriles, showcasing broad substrate scope. Please have a look: pubs.acs.org/doi/10.1021/ac…

Our heartiest congratulations to all the winners of the 'OPPI Scientist Award 2023' at the #OPPIAnnualSummit. You’re all an exemplary example of excellence & perseverance, lending your expertise to the further development of India’s healthcare ecosystem. #BharatKeLiye

Nucleoside-Derived Metallohydrogel Induces Cell Death in Leishmania Parasites | ACS Infectious Diseases pubs.acs.org/doi/10.1021/ac…

Nucleic acids as templates and catalysts in chemical reactions: target-guided dynamic combinatorial chemistry and in situ click chemistry and DNA/RNA induced enantioselective reactions - now published in Chemical Society Reviews pubs.rsc.org/en/content/art…