David Mauduit

Happy to share CREsted, our latest package on enhancer modeling! CREsted allows for training sequence-based deep learning models from scATAC-seq data, enhancer decoding and enhancer design through a variety of methods. Check out the GitHub here: github.com/aertslab/CREst…. [1/9]

Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex biorxiv.org/cgi/content/sh… #biorxiv_genomic

Watch the #SpatialOmics24🎦pitch by Nikolai Hecker of the @steinaerts lab at @_VIB_AI. In it, he reveals the similarities between the bird and mammalian telencephalon using spatial #transcriptomics and #singlecell #multiomics-derived enhancer codes.

We're at the #VIBseminar24 today! Fantastic to open this general assembly with a session on AI & Computational Biology and an intro on @_VIB_AI's mission and unique approach. 🧑‍💻✨

New study from the lab led by @niklaskemp and Nikolai Hecker. Very happy to have been part of this work!

Excited to announce our upcoming webinar on SCENIC+: a Python package for constructing enhancer-driven gene regulatory networks from single-cell multiomics data! Join us on March 26th, 5pm CET. Register here: forms.gle/cVP3tW17fnJY4b…

1/11 Check out our preprint introducing Nova-ST, a high resolution, spatial barcoding workflow developed by repurposing Illumina’s NovaSeq 6000 S4 flow cells for spatial transcriptomics profiling. biorxiv.org/content/10.110…

📣 New paper alert! The @steinaerts lab shows that deep learning models can be used to efficiently design synthetic, cell-type specific enhancers, starting from random sequences. 🧬 (1/3)

🤖🧬In a new breakthrough, the team of @steinaerts (@_VIB_AI, @CBD_VIB) designed an AI model to guide the creation of synthetic DNA sequences. The study enhances our understanding of gene regulation and holds great potential for gene therapy. Read more: vibbio.tech/3t5sZdv

Very proud to have been part of this awesome project!

📣 We're excited to announce the opening of multiple faculty positions! Do you use and/or develop artificial intelligence methods and mechanistic mathematical models to address fundamental questions in biology? We'd love to hear from you. (Please share far and wide 🙏)

@PenguinUKBooks Is it sewn or glued binding?

Just LOOK at the new Vintage Quarterbound Classics collection 😍 Out this October 👉 bit.ly/48d6Klz

📚 GIVEAWAY 📚 It's National Book Lovers Day! To celebrate, we're giving one of you a chance to win a £100 Folio gift card. TO ENTER: Follow @foliosociety and retweet this post. Open internationally. Competition closes 23:59 (UK time) Sunday 13 August

Happy to announce that our latest work on deciphering enhancer grammar in the mouse liver is out @steinaerts #HalderLab! Link: biorxiv.org/content/10.110… 🧵 1/12 🧵

I'm happy to share my Postdoc work in the @stark_lab on mapping and unravelling the regulatory specificities between corepressors (CoRs) and active enhancers (1/4)

🎂 COMPETITION 🎂 To celebrate our 75th anniversary, we’re launching the most exciting competition in Folio’s history... One lucky Folio fan will win their choice of 75 different Folio editions! To enter: RT this post and follow @foliosociety.

We're hiring: jobso.id/f5d6! Looking for a wet-lab #scientist to head our work in tumor evolution at @vib_ccb & @Onco_KULeuven for years to come. Interact with bioinformaticians, clinicians & @VIBTechWatch while tinkering with @nanopore + #SingleCell #sequencing tech.

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks biorxiv.org/cgi/content/sh… #bioRxiv

Happy to announce that SCENIC+ is out! SCENIC+ is a new workflow to infer enhancer-driven gene regulatory networks from scRNA-seq and scATAC-seq data. Great work with @Bravo_Potato at @steinaerts lab! 🧵 1/11 🧵.