Dean Pontius retweetledi
We are excited to announce we have achieved the first-ever therapeutic #RNAediting in humans in our RestorAATion-2 trial of WVE-006 in Alpha-1 antitrypsin deficiency. Learn more. #AATD $WVE
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Dean Pontius
87 posts
Dean Pontius
@DeanPontius
Molecular medicine PhD student @ClevelandClinic/@CWRUSOM. @CaseEngineer alumn.
Cleveland, OH Katılım Haziran 2017
475 Takip Edilen157 Takipçiler
Dean Pontius retweetledi
A recent commentary in bioRxiv discussed data analysis for our mtDNA-based lineage tracing technology ReDeeM. We welcome the points raised and are happy to address these concerns. We believe this will foster constructive dialogue (1/n) doi.org/10.1101/2024.0…
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Dean Pontius retweetledi
Want to support student lead research in CLE?
Students in the 'Life as a Scientist' program are finishing their grant proposals! Once awarded, we supply all of the equipment, materials, and professional support they need to complete their project.
riseupnortheastohio.org/donate
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Dean Pontius retweetledi
Excited to share a favorite project, now out on @biorxivpreprint . biorxiv.org/content/10.110… This has been a big undertaking for the past couple years: two (!) year-long rounds of retinal organoid differentiation by Laura Bohrer... (1/8)
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Dean Pontius retweetledi
📢 Preprint alert! 🚨 Superstar postdoc, @marissascavuzzo, leads our latest work titled "Enteric glial hub cells coordinate intestinal motility".
Marissa is a @HHMInews Hanna Gray Fellow and a former @NYSCF Druckenmiller Fellow.
🙌Read the study here 👇
biorxiv.org/content/10.110…
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Great to see this out - awesome work by twitterless lab mate Devin Neu!
bioRxiv@biorxivpreprint
Oncogenic reactivation of young L1s is a hallmark of colon cancer biorxiv.org/cgi/content/sh… #bioRxiv
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Thanks @michael_hoerger for the shout out! So excited to share that I’ll be returning to #NOLA in July to help grow the new CHOICES center @TulaneMedicine. Huge thanks to my wonderful research team and fellowship @MSSatNU for all their guidance and inspiration these past 2 years!
Mike Hoerger, PhD MSCR MBA@michael_hoerger
Great news for Louisiana! ⚜️ Our 1st #HealthPsychology PhD graduate is returning to Tulane as an Assistant Professor in the new "Center for Health Outcomes, Implementation and Community-Engaged Science" (CHOICES) program. Congratulations Dr. @Perry_LM!!! 🎉🎉🎉
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Dean Pontius retweetledi
Glad to share our new paper describing gene expression changes in single RPE cells between regions of the retina. I hope this can be a useful dataset for others studying macular disease! Data are also available for your perusal on singlecell-eye.org!
pubmed.ncbi.nlm.nih.gov/36775060/
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Dean Pontius retweetledi
Really excited to share my first first-author @biorxivpreprint from my thesis work from @TesarLab. Thanks to everyone involved!
Paul Tesar@TesarLab
Excited to share a new @biorxivpreprint "Pervasive environmental chemicals impair oligodendrocyte development" led by a superb MD/PhD @CWRUmstp student, Erin Cohn @ErinFCohn. We appreciate all feedback on this surprising (and sorta scary 😱) study. biorxiv.org/content/10.110…
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Dean Pontius retweetledi
Dean Pontius retweetledi
🔌⚡️🏘️
Excited to share our new @biorxivpreprint: "Non-random distribution of mitochondrial m.3243A>G heteroplasmy in human retina and its impact on cellular phenotype."
biorxiv.org/content/10.110…
Question: how does mtDNA distribution inform mitochondrial disease phenotype? 🧵👇
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Dean Pontius retweetledi
Very excited to be elected as a Senior Member of the National Academy of Inventors @AcadofInventors. I hope that past, present, and future innovations from the @TesarLab will make a difference for patients and their families.
National Academy of Inventors@AcadofInventors
It is our distinct pleasure to announce the election of the Class of 2022 #NAISeniorMembers! We congratulate this Senior Member class, well on their path of prolific discovery, and welcome them into the NAI Community. See the full Class of 2022: ow.ly/ieZa50HR5W2
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Dean Pontius retweetledi
Happy to share our recent foray into mitochondrial genetics out in @hmg_journal! Here we used digital PCR to relate peripheral m.3243A>G heteroplasmy to the presentation of visual symptoms. I am excited to keep learning more about this fascinating field!
academic.oup.com/hmg/advance-ar…
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Dean Pontius retweetledi
Please share/retweet: @QBI_UCSF is hosting an event for Native/Indigenous biomedical scientists lead by @willowcoyote. We are looking for undergrad, grad student, and postdoc Native speakers! Deadline is September 1st to apply for a talk!
qbi.ucsf.edu/Native-Indigen…
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Dean Pontius retweetledi
Our studies are expanding from cancer into other major public health crises. Check out our latest on opioid use disorder. Team effort with Akbarian, Johnson, Mash, and @CorradinLab. biorxiv.org/content/10.110…
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Dean Pontius retweetledi
Delighted to share our work studying the molecular control for the directed β cell differentiation process @NatMetabolism
nature.com/articles/s4225…
Great collaboration with Jiajia Xi @FulaiJin lab and Yan Li lab @CWRUSOM.
GIF
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Dean Pontius retweetledi
New paper from our team out today in @CellStemCell. In this work we show the mechanism by which low oxygen damages myelinating cells in the brain and reframe therapeutic strategies for combatting hypoxia-mediated disease.
cell.com/cell-stem-cell…
A thread…
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@GI_Zhou @NewYorker Desserts have definitely gone downhill recently
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The tiramisu at Leo, in Brooklyn, comes in a fluted glass tumbler that showcases its appealingly messy striations, as spoonable as pudding. nyer.cm/S8gvDen
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