Denis Wakeham

Our latest cover image comes from this article from @DenWakeham (@UTSWMedCenter) et al., as they set out to determine if it is possible to assess #aortic stiffness from standard #cardiac MRI. 📜 buff.ly/fvmdU4S

New by @GManferdelli and colleagues in HAMB Ignoble Gas: The Questionable Role of Xenon in Rapid Ascents of Mount Everest liebertpub.com/doi/10.1177/15…

Collected some our of thoughts regarding heart-lung interactions during exercise in patients with HFpEF in Heart Failure Reviews. Really, a lot of unknowns in both healthy and clinical populations. Bonus points if you catch the lyrics ;) link.springer.com/article/10.100…

Earlier this year, Xenon was described by media as the missing piece to climb Everest faster and safer......Scientific evidence suggests it is not❌ Ignoble Gas: The Questionable Role of Xenon in Rapid Ascents of Mount Everest #utm_source=FastTrack&utm_medium=email&utm_campaign=ham" target="_blank" rel="nofollow noopener">liebertpub.com/doi/abs/10.117…

Mini-Review by @N_A_Carlini et al. (@UVRLphysiology @K_Bunsawat @UUtah @CUAnschutz @uiowa) #Vascularfunction in women with #heartfailure with preserved #ejectionfraction: a mismatch beyond #diastole ow.ly/bPQU50WTu5Z

Really happy to see this published in EJHF. Joey, Chris and I show that middle-aged adults with severe obesity present with absolute hypervolemia, relative hypovolemia and disproportionate LV enlargement. @utswheart @UTSWMedCenter @texashealth @IEEMPHD doi.org/10.1002/ejhf.7…

Great work from @AlexSullivan_MD, @JoshuaBeckmanMD & others. Really glad to be involved with this great team and important work. Much more to come from @JoshuaBeckmanMD, myself and our colleagues in the @UTSWMedCenter Division of Vascular Medicine.

🚨Funded PhD opportunity @LboroSSEHS - starting October 2025! 🔓Exploring iron status and supplementation in athletic individuals. ✨Supervisory team: myself, @LJJ_nutrition and Lettie Bishop. 🔗 lboro.ac.uk/study/postgrad…

Research Article by @ZachMcKenna_PhD et al. (@whitleyatkins) Evaluating low-energy cooling strategies on #thermal and #cardiacstrain in older adults exposed to very hot and dry heat with accompanying activities of daily living ow.ly/NV2r50WsP77

What is the contribution of abnormal lung mechanics to the rise in ventricular filling pressures in HFpEF during exercise ? Elegant work by the IEEM @UTSWMedCenter on the study of hemodynamics, lung mechanics and HFpEF now in @JACCJournals #JACCHF 📎 jacc.org/doi/10.1016/j.…

Really happy to see our paper published in @JHypertension. @Deoliveiragdc and I show that the BP pressure response to exercise is not different between hypertensive adults with LVH and healthy controls when normalized for VO2. journals.lww.com/jhypertension/…

Julian C. Bommarito & Philip J. Millar (@UofG_HHNS) offer this #Perspective 'Metabolic override: Adding neuropeptide Y to the list of vasoconstrictors attenuated by exercise' based on the work of Wakeham et al. (2025) 💭 🔗 buff.ly/f7UxgmD

New in @japplphysiol by @ZachMcKenna_PhD and colleagues Evaluating low energy cooling strategies on thermal and cardiac strain in older adults exposed to very hot-dry heat with accompanying activities of daily living journals.physiology.org/doi/abs/10.115…

In this recent study, Denis J. Wakeham (@UTSWMedCenter) et al. investigated functional sympatholysis of neuropeptide Y-mediated #vasoconstriction in humans 🫀🏃 📜 Read the #Research here: buff.ly/VYNVPm9

Happy to share our recent paper published in @JPhysiol that shows, for the first time in humans, that Neuropeptide Y mediated vasoconstriction is sensitive to functional sympatholysis, to a similar degree that is alpha-adrenergic vasoconstriction. physoc.onlinelibrary.wiley.com/doi/10.1113/JP… First of many papers in this area from Chris M. Hearon Jr.'s lab at @IEEMPHD (@texashealth) and @UTSWMedCenter. Thanks to our collaborators, Paul Fadel and Scott Davis, on this project.

Congratulations to @JoshuaBeckmanMD, whose visionary leadership as chair of the AHA/ACC Joint Committee on Clinical Practice Guidelines makes him more than deserving to be honored with an Award of Meritorious Achievement. The improvements Dr. Beckman spearheaded in the guidelines development process will continue to profoundly benefit providers and patients for many years to come. spr.ly/6018Nfs7A #AwardsWithHeart

Great to see this published in @ExpPhysiol working with Mike Nelson. The paper extends the assessment of central arterial stiffness and wall mechanics (strain and strain rate) from ultrasound to MRI using a cine collected in every cardiac MRI ever taken. doi.org/10.1113/EP0925…

🌟 PhD Opportunity Alert! 🌟 Dr. Matt Armstrong, who directs The Applied Vascular Physiology Lab at Syracuse University, is recruiting a PhD student (fully funded) for an exciting project aimed at improving the assessment of cardiovascular age and understanding its impact on long-term health. 💡 Join the lab to: - Develop innovative methods for analyzing arterial waveforms. - Explore the relationship between vascular aging and cardiovascular risk. - Contribute to creating accessible tools for improving health outcomes. 📍Based in Syracuse, NY, this is a unique opportunity to advance cardiovascular science and make a real-world impact. Interested? Reach out to Dr. Armstrong at cardiovascularlab@syr.edu to learn more! Please retweet. @NAASociety @ArterySociety @APSPhysiology @physoc @American_Heart @ACSMNews @E_C_S_S #CardiovascularResearch #HealthInnovation #ScienceCareers #PhDposition