Denis O'Meally

Pleased to present "genome assembly for the Australian alpine skink Bassiana duperreyi" biorxiv.org/content/10.110… . High heterozygosity, centromeric satellites of 187 & 199bp, rDNA at ~15kb. Great resource for sex determination and chromosome evolution in skinks and other lizards

Q: What could GO WRONG with a major cancer genomics study in which tumours are sequenced to only 15x depth? A: An awful LOT! 😟 Our detailed reanalysis now out in @RSocPublishing: tinyurl.com/RSOSrebuttal 🧵👇 (1/18)

Happy to share our new paper “Transcriptome free energy can serve as a dynamic patient-specific biomarker in acute myeloid leukemia”. A fantastic collaboration with @rrockne, @lisauechi, @SwethaVasudeva4, and the @cityofhope researchers. @Nature_NPJ nature.com/articles/s4154…

Erm, how did Figure 1 get past a peer reviewer?! frontiersin.org/articles/10.33… H/T @aero_anna

Out today! We create a CML potential landscape from time-series whole transcriptome data and use math modeling to predict disease onset and treatment response from a single pre-disease time point. (1/2) nature.com/articles/s4137… #scicomm #mathonc @cohmathonc

We're honoured to present @DrRebeccaJ with an inaugural Embassy of Australia Award. This trailblazing 🇦🇺 has the coolest job in Washington: Chief Scientist at the Smithsonian @NMNH. She led research into the Koala Genome, and is recognised as a superstar of STEM. 📷 Nick Langley

Exciting opportunity: @NCIG2013 is #hiring #postdoc #ResearchFellow in #pharmacogenomics @ourANU @JCSMR Apply at tinyurl.com/ncigJob3 #AcademicJobs #bioinformatics #genomics DM for info/questions, generous renumeration, international applicants welcome

Check out our latest preprint using stochastic modeling of the full time-series transcriptomes to better understand leukemia! 🧵 below, but first, the three key take-aways: biorxiv.org/content/10.110…

#JobOpportunity! 💻🧬 at @WEHI_research - #singlecell Large-data #Analytics - #SoftwareEngineer - #HPC Work with us and @CSL to make the next-generation #singlecell immune-intelligence infrastructure! 🗓️ by 26 Oct Community, please RT! wehi.wd3.myworkdayjobs.com/WEHI/job/Parkv…

🎉🧹 The #tidyomics ecosystem is official! Into #omic data analysis? Spanning #Seurat @Bioconductor #SCE, #SE, #GRanges, #Citometry? Now, just use #tidyverse ! Co-led with @mikelove and @TonyPapenfuss @WEHI_research #singlecell The preprint biorxiv.org/cgi/content/sh…

NOW OUT @ScienceMagazine 🧬🐾🤓 “The evolution of two transmissible cancers in Tasmanian devils” A 🧵 on our deep DNA sequencing dive into the startling genetic history of contagious tumours (1/n) 👇 doi.org/10.1126/scienc…

Museum collections provide some of the most important data to help us understand and predict what is happening under a changing climate. However, our collections pre-date electronic databases by hundreds of years so how do we know what we have?

See our collaborative paper where we surveyed for some expected and unexpected #virus #chlamydia #pathogens in our Australian #birds #parrots #pigeons #kingfishers #Raptors Supported by @arc_gov_au BirdsQueensland @usceduau @wildwarriors @VirusesMDPI 👉🏽mdpi.com/1999-4915/15/1…

Timeline cleanse courtesy of my Pit Bull/German shepherd/Shitzu 🐾🐾❤️

@DumindaSb @ardynasios @HolleleyClare @j9deakin @MVLizards @joanna_sumner99 Congratulations Dumi!

It was fantastic to hand over the final copy of my thesis to my primary supervisor. A massive thank to my supervisors and collaborators for everything during this epic journey, with @ardynasios @HolleleyClare @j9deakin @MVLizards @joanna_sumner99 @DenisOMeally

Check out our new paper in @ScienceAdvances! We show that the microRNA (miR) transcriptome undergoes a state-transition during AML development. Here's a thread on the main take aways on how we used the state-space to learn about AML. 🧵👇 science.org/doi/10.1126/sc…

Kinks in chromosomes cause sex in this crazy cute lizard; our new paper in PNAS: pnas.org/content/119/4/…

Specks of dust on the microscope slide? No, we are looking at the building blocks of our genome theconversation.com/specks-of-dust… via @ConversationEDU

So pleased to publicly release the first 116 koala genomes on @AWS today! Huge effort from our team @KathyBelov @lukesilver20 Konnie, Kim, @ellemclennan & researchers who provided samples! Thanks @Matt_KeanMP @sussanley for funding. @Sydney_Science aboutamazon.com.au/the-450-koalas…