Joe Whittaker
3.9K posts
Joe Whittaker
@DiagnosticsJoe
Hockey player for @cambsouthhc. Also... a blogger and tweeter about #genomics and a marketer of #NGS at @nanopore. Ex @illumina . Views are my own.
Cambridge, England Katılım Ocak 2015
1.2K Takip Edilen7.2K Takipçiler
Just doubled my long read sequencing capacity.
Oklahoma City, OK 🇺🇸 English
Joe Whittaker retweetledi
Mmmmm, fresh genome. This is a peek at the nanopore data ahead of Illumina run next week. Amazingly fast turnaround time of TWO DAYS. Thanks, @plasmidsaurus!!! Already designing knockout cassettes as we speak. Engineering microbes for nice smells at @SenseoryPlants.
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Sebastian S. Cocioba🪄🌷@ATinyGreenCell
Anyway, gonna try out @plasmidsaurus's hybrid genome sequencing for a work microbe I'm developing at @SenseoryPlants. Price seems decent. Let's see how good the coverage is on this 7ish Mbp actino. We'll upload genome to genbank once assembled and polished. Yay, sequencing!
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Joe Whittaker retweetledi
What happened when scientists at @UnivReims tested 241 samples from 11 French clinical diagnostic labs using the #AmplideX @Nanopore Carrier Plus Kit (RUO)?
Check out the #AMPath24 poster from @aslebre_genet et al: bit.ly/3Wg5U2W
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Joe Whittaker retweetledi
a novel tool! PRONAME: a user-friendly pipeline to process long-read nanopore metabarcoding data by generating high-quality consensus sequences. #nanopore #metabarcoding dx.doi.org/10.3389/fbinf.…
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Using 'only' a MinION device with adaptive sampling to generate long reads. Pocket-sized cancer detection for you🔥🔥
Oxford Nanopore@nanopore
Hanlee Ji and team are unlocking the mutational landscape of cancer at single-cell resolution. From BCL2 fusions to KRAS mutations — read how they’re revealing more about tumour heterogeneity: bit.ly/4ilS4FM
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Joe Whittaker retweetledi
Excited to share our new study of #genomics🧬, #EHR📈 + treatment outcomes of 78K patients across 20 #cancers!
We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who respond well to immunotherapy #precisioncancer
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Nice. I remember doing a BBSRC summer internship in the UK on wheat varieties and the affect of take-all on them....both by hand, visual scoring, and a few basic molecular techniques...! 🤣
How times have changed in Ag!
Earlham Institute@EarlhamInst
Scientists from the Earlham Institute will head to #PAG32 next month, presenting their work during the '#wheatgenomics to breeding' session on using #genomeassemblies and ultra-long #Nanopore reads to identify key variations in wheat. okt.to/vE34sY
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Joe Whittaker retweetledi
Joe Whittaker retweetledi
Tis the season for #holiday lights. #avianinfluenza sequencing up and running on our new #mk1d from @nanopore at @PasteurCambodia . #nanopore #oxfordnanopre #genomic #h5n1 #alliwantforchristmas #anywhereanything
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Joe Whittaker retweetledi
Excited to show our latest attempt at a clinically meaningful clinical cancer genome with rapid turn around (24 hours!) times using Oxford Nanopore sequencing technology for patients who need a rapid, whole genome assessment of their tumour and germline, offering them (1/n):
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Joe Whittaker retweetledi
Joe Whittaker retweetledi
PromethION 2 Integrated (P2i) is moving to open early access.
With its onboard compute and integrated screen, the self-contained device is bringing high-quality, real-time sequencing to a wider range of labs.
Learn more: bit.ly/48PDCQ9 #WYMM
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Joe Whittaker retweetledi
Direct RNA sequencing update!
We are pleased to announce that RNA004 is moving into open Early Access.
RNA004 provides higher outputs and accuracy compared to the previous version RNA002.
Learn more: bit.ly/40KRtVI 1/9
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Joe Whittaker retweetledi
Great accuracy using @nanopore DRS RNA004 on total RNA. ~96-98% identity using sup calling. Example of a ~10.8 Kb full length 🥬 transcript below. 💥
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Joe Whittaker retweetledi
Well here's the @nanopore update.. we have carried out a hereditary cancer panel screen:
* ~200 genes
* 15mbases panel
* Coverage between 50-70x on target; 5x off target
* 16hr run time LSK114 + R10.4.1
This is PMS2 exon 10&11 - a notoriously difficult place to sequence with SR
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Joe Whittaker retweetledi
