Brian Carson
5.1K posts
@DrBPCarson
Professor in Exercise Physiology with interests in metabolic health and human performance. Views my own.
Inhibition of mTORC1 by rapamycin results in feedback activation of AktS473 and aggravates hallmarks of osteoarthritis in female mice and non-human primates “Systemic rapamycin treatment worsened hallmarks of OA in female mice and marmosets. Specifically, rapamycin increased age-related meniscus calcification in female marmosets and exacerbated meniscus calcification and cartilage pathology…” biorxiv.org/content/10.110…
@NSCA President Prof. Ian Jeffreys presenting @DrDavidNolan & @irishscnetwork the President's Award in celebration of this year's @irishscnetwork conference!
Hey Muscle And Metabolism Folks on Twitter, @LykkeSylow and I are looking for a Postdoc who is interested in applying for a prestigious @DDEA_Denmark fellowship with us. More details in the picture attached. Please share widely! @MYOTWlTTER
I was interviewed for a New York Times article a little while ago and never shared it because #impostersyndrome 😋 and weirdly scared of public recognition (despite wanting to grow in science communication lol….) but I should be excited to share something like this. Thank you, @sweatscience for letting me be a part of this piece!! 🙏🏼 (& my very generous supervisor who passed this opportunity onto me) Very grateful to be included. nytimes.com/2025/02/19/wel… I can’t confirm I said the exact quote implying Zone 2 is useless for mitochondrial health haha it’s a very strong statement that makes me a bit uncomfortable BUT here’s what I do think: - Your Zone 2 workouts are not doing anything inherently beneficial to mitochondria or ability to burn fat that you couldn’t achieve with higher exercise intensities (in less time) - And it is very possible that purposely foregoing higher exercise intensities for Zone 2 could limit potential for mitochondrial adaptations that could otherwise be gained by accumulating time spent above Zone 2 In the latter case, I think there is potential harm in pushing the narrative to the general population that we all need to be dedicating time to Zone 2 exercise if the goal of exercise is to induce these adaptations that promote better health. Publication to support this position coming soon (accepted in Sports Med).
