Dr Silverstone

@anishmoonka Me reading this as a medical doctor on a night shift.

You make a cancer-fighting chemical in your brain every night. It kills tumor cells and fixes broken DNA while you sleep. Only works in the dark. The hormone is called melatonin, and when you flip on the lights at 2 AM, your brain stops making it. Melatonin is the sleep hormone. But it moonlights as your body’s overnight cancer patrol. It chokes off the blood supply to tumors and wakes up your natural killer cells (the white blood cells that hunt down cancer). Melatonin also flips on genes that order damaged cells to stop dividing. Researchers at Tulane ran an experiment where they exposed rats to dim light at night. Not bright light. Dim. The tumors lost their natural growth rhythms and grew nonstop. The WHO classified night shift work as “probably carcinogenic” in 2007. Reviewed everything again in 2019. Kept the classification. Same risk category as UV radiation. Your body’s internal clock controls more than when you sleep. It schedules DNA repair. There’s a repair protein called XPA that rises and falls on a 24-hour cycle, timed by your clock genes. When scientists knocked those genes out in mice, DNA repair went haywire and tumors grew faster. The same clock decides when damaged cells kill themselves off before they turn cancerous. Wreck the clock, you lose all of that. Denmark started paying workers’ comp for this. In 2008, the Danish government said: if you worked night shifts at least once a week for 20+ years and got breast cancer, that’s an occupational disease. Between 2007 and 2011, 110 women got compensated. One was a flight attendant who did 30 years of overnight flights for SAS airlines. No other country has followed. 1 in 5 workers worldwide works night shifts. In the US, that’s around 15 million people, mostly in healthcare, factories, and trucking. The exposure tilts hard toward people who can least afford it: 20% of workers without a high school diploma pull non-daytime shifts vs. under 2% of college grads. I’ll be straight with you, the science isn’t totally settled. A big 2020 analysis pooling 57 studies and 8.5 million people found no clear overall link between night shifts and cancer. But a 2024 study tracking how risk changes with time on the job told a different story: 9% higher breast cancer risk after 20 years of night work. 13% higher after 30. The lab evidence in animals is clear cut. The human data is messier, the way it always is when you’re studying something millions of people do in a thousand different ways.

@Jessseglee My Chief! Congratulations 👏🏾

@lifeofdanel The fuck? 😂

Sometimes your fooling on the TL dey make me forget say you be chef. But your meals always look delicious and attractive. I can't wait to be in your location someday and get to taste your juicy meat.

@DavidKPiano Banger 😂

Ironically this is probably the first time that actual humans are carefully & thoroughly reviewing the Claude Code codebase

@DavidKPiano 😂😂😂

There is a project on GitHub called Axios. Axios is extremely popular. It is used by millions upon millions of applications. Axios is a programming library that helps your JavaScript code make HTTP/S requests (communicate with websites). In simple terms, if you're a programmer doing something with JavaScript, and want to do stuff that communicates with a website in literally any capacity, people heavily recommend using Axios due to its simplicity. Using Axios you don't have to reinvent the wheel and do a bunch of work. All you need to do is import Axios into your code and you're off to the races. Someone (currently unknown) compromised Axios (currently unknown how) to deliver malware to people. When someone updates or installs Axios, Axios itself contains malware. What the malware does is (currently) unknown, but it is being reversed engineered by probably every malware analyst on the planet at this moment. In a few hours more details will emerge. Information is being exchanged in real time on social media and private communication platforms as I write this. Due to the size and popularity of Axios, it is unknown how many are impacted, it could be millions, it could be thousands, or if we're lucky, only hundreds of people or organizations will be impacted. If this is absolute worst case scenario, millions of organizations across the planet have been infected with malware which (currently) we do not understand. However, the likelihood of this is low. It appears Axios being compromised was detected quickly, potentially within minutes (or hours) of it being compromised to deliver malware. Additionally, the likelihood of every single Axios user updating Axios as soon as it was compromised to deliver malware is astronomically low. It is basically zero. The impact from Axios being compromised is devastating, the fallout from this will be a massive headache. This is unironically a malware nuclear missile and will likely be studied in the future.

If you sometimes feel like you’re too ambitious and would rather just take things a bit slower and settle for average, don’t do it! One day you’ll look back and won’t forgive yourself for not getting much more from life when you know you could have achieved a lot more. People will try to convince you that you’re doing well already, but remember that they’re judging you by their own abilities. You’ll hate yourself if you underachieved. No amount of external validation will compensate for the person you did not become despite the potentials and abilities.

The next phase of this is a free tool to help junior doctors know what to do based on treatment guidelines, and can check the reference to see the exact page in the guidelines. Still in development. What features would you like to see and what guidelines should I add?

Emeka's startup processed 50,000 naira every minute. Then TechCabal featured them. In 4 minutes, everything was gone. The database. The payments. The investors' trust. All because of one backend concept every Nigerian engineer skips. Let me show you what killed them.

I’ve always felt my career trajectory was a bit of a gap away from the norm. Instead of going deep into just one niche, I’ve followed my curiosity across technical project management, community building, and infrastructure. Defining what you do is tough when you’re working at the frontier of new innovations, but I’m grateful to @TechpointAfrica for helping me tell my story. From bricking my first Android phone to building Africa’s first DeSci ecosystem—it’s been quite a ride. Hope you have a good read!

Here's a detailed breakdown of how I built the NSTG dataset:

The goal right now in the healthcare space is to go from cool demos to building stuff people actually use, and the foundational layer is extremely important for that..

@knightofdelta 🙂 I just finished medical school. I don't want to ever be in this situation in 10 years time.

I finished medical school about a decade ago. My classmates just raised about N2 million to provide medical support for one of us. I don’t want to convert to USD. I just wanted to note that he served Nigeria with his medical skills. N2 million. Let that sink.

I don't think it's an issue. The end users don't care. @FirstBankngr has a horribly designed interface and people still use it. If the customer is satisfied, and it still converts I don't think think it's an issue

@Rxbremen Bremen, this is incredible. I want to read this.

I have been writing a report on Jumia Nigeria and it’s larger group for the past 2 days I’m not done. One thing I can say is, ideas like this are only good on paper unless you are ready to do the work which often involves burning cash, or in best case scenario there are market leaders who have already established blueprint and reliable framework. If I told you as big and as massive as Jumia is, they have never made profit, in 14 years of running the business? I added two excerpt just for context sake, business management and operations are always way complex than ideas that sound bright.

@Ssaasquatch Plain Bagel. Patrick Boyle, Tayo Aina >>

YouTube is easily my favorite app. I spend at least 20+ hours on it every weekend. One minute I’m learning how to value the most complex derivatives instrument just for the fun of it and the next minute, I’m halfway across the world through a travel vlog experiencing cultures I’d never otherwise see…..all from the comfort of my apartment. Today’s destination: Papua New Guinea

Pure Genius. Well-done brother!

@ez0xai 1. Change the name. 2. Your verify screen should be the first screen. I know you built this for developers, but the general public would want to go to the site and quickly verify it Otherwise, incredible work my friend

Shipping big things on 9jaCheckr.xyz very soon What features would you like to see?

just used 9ja Checkr telegram bot to verify my drink's NAFDAC number lol works instantly try it: t.me/NaijaCheckrBot 9jaCheckr.xyz

@ruthefordml Imagine the implications for healthcare apps. EMRs for Pharmacies.

@DrSilverstone It is!

Fucking incredible.