EXCLI Journal

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#Leber's hereditary #optic #neuropathy (#LHON) causes inexorable painless vision loss. excli.de/index.php/excl… provides valuable insight into LHON #genetic #predisposition, particularly in cases lacking primary #mtDNA #mutations. #Aravind Medical Research Foundation

😁🎉😄🌟#NobelPrize!🙃🙃🙃🙃🙃🙃🙃🙃🙃🙃🙃😊🏆😁#PhysicsNobelPrize2023 for Ferenc Krausz, Max Planck Institute of Quantum Optics! 🎊😃🥰😆🥳😁😃🎉🏅😊🎈😁🥳😄🎊😁🌟😃🥰🏆😁🎉🎇😊🥳😄🌟🎈😁😃🥰🎉🏆😁🎊😊😄🥳🌟🎇😁🥰😃🎉🎈😁🏆😊😄🎊🥳😁🌟😃🥰🎉🏅😁🎈😊🥳😄🎉😁😍😁🎉🎇😊🥳😄🌟🎈🏆

#Obesity and #diabetes mellitus - major concern to modern societies. #Community-based screening is an effective strategy to identify people at high risk excli.de/index.php/excl… presents the results of screening the population in the #Ivano-Frankivsk region @pnu_edu_ua @Carleton_U

Risky-choice framing effects excli.de/index.php/excl… indicates that the existence of #framing effects points to the adaptiveness of the processes underlying #human judgment and choice rather than simply showing #human irrationality @PLUS_1622

#Antimicrobial resistance (#AMR) #Drug discovery of inhibitors against novel targets rather than #conventional #bacterial targets has been considered an inevitable strategy for the growing threat of #infections: excli.de/index.php/excl… @MahidolU @BezmialemBilsab @SnowflakeDB

#Non-alcoholic fatty liver disease (#NAFLD) is a prevailing health challenge that requires urgent innovative interventions. excli.de/index.php/excl… explores the role of #nanotechnology as a promising potential in the treatment of NAFLD. @kauweb @DaffodilIqac

Effects of #posttraumatic stress disorder (#PTSD) include chronic activation of the #sympathetic nervous system (#psycho-emotional stress) excli.de/index.php/excl… discusses PTSD as a disease with its #neurological, #immunological, and #metabolic components @pnu_edu_ua @Carleton_U

Crucial information for the development of more accurate and efficient druggable #protein #predictors delivers a comprehensive survey regarding the state-of-the-art #computational approaches for in #silico prediction of druggable proteins. @MahidolU excli.de/index.php/excl…

The development of #PCL (#phosphatidylcholine) fortified nano-phytopharmaceuticals presents a promising opportunity to enhance the therapeutic efficacy of plant-based medicines. @Ganpat_Uni @cmuofficial_tw excli.de/index.php/excl…

📣 SAVE THE DATE📣 Am 26.09.23 um 18 Uhr laden euch die Stadt Dortmund und das IfADo zum Science Slam im Projektor ein. Vier Wissenschaftlerinnen erklären in unterhaltsamen Vorträgen komplexe Zusammenhänge und zeigen, wie spannend Forschung sein kann. Einlass ist um 17:30 Uhr.

Upper #gastrointestinal bleeding due to #Dieulafoy’s lesion of the stomach Read this case report here: excli.de/index.php/excl… @RCSI_Irl

#Urinary #bladder #cancer, #smoking, #occupation Course of the disease on 712 bladder cancer patients and 875 controls from 3 #case control studies distinguishing between #muscle invasive (#MIBC) and #non-muscle invasive bladder cancer (#NMIBC) excli.de/index.php/excl… @IfADo_info

Zinc in #human health excli.de/index.php/excl… aims to explain the involvement of #zinc in specific health conditions such as #cancer, #COVID-19 and #neurological disorders like #Alzheimer's disease, as well as its impact on the #gut #microbiome @uoaofficial @upatras @EIEgr

May there be a trade-off between #learning efficiency and the ease of generating new information? excli.de/index.php/excl…: Exploring #cognitive individuality and the underlying creativity in #statistical learning and #phase entrainment @UTokyo_News_en

#Cardiac #amyloidosis - evolving #pathogenesis, #multimodal diagnostics, and principles of treatment excli.de/index.php/excl… compiles comprehensively the #pathophysiology and clinical picture of cardiac amyloidosis subtypes, extending a clinically oriented approach @kauweb

#Circulating #tumor #DNA (#ctDNA) as a promising approach for cancer diagnosis - a focus on #hepatocellular #carcinoma (HCC) excli.de/index.php/excl… discusses the HCC-related mutated genes diagnosed by ctDNA and presents different ctDNA diagnosis approaches #screening #biomarkers

Relating #aging and #autophagy - a new perspective towards the welfare of #human #health excli.de/index.php/excl… aims to look into the role of autophagy in aging and how it can be used to improve one's health @JUFET #misfolded #protein

No specific treatment or #vaccine available against the #chikungunya virus (#CHIKV)? excli.de/index.php/excl… reveals #flavonoids isolated from Marcetia taxifolia could be promising anti-CHIKV therapeutic agents @UANTONIONARINO @UPTCoficial @unisalle @UCV_Noticias @IVIC_oficial

Novel strategies are necessary to target underlying #cardiovascular disease mechanisms. excli.de/index.php/excl… reviews innovative #therapeutic strategies into #clinical care for #cardiovascular #disorders. #AMPK #apoptosis #autophagy #FoxO #NAD+ #SIRT1