Emilie Mace

1/8. Preprint!✨How spontaneous is spontaneous behavior?🧠🐭 We found that whole-brain fUSi signals predicted spontaneous behavior transitions seconds in advance. Inhibiting one node of this transition-prone state, the medial septum, facilitated switching! biorxiv.org/content/10.648…

👁‍🗨We turn science into sight. Congratulations to our Director @IOB_Roska on receiving the 2026 Future Vision Award alongside Connie Cepko & Daniel Ting. A recognition of long-term research now reaching patients. 🎬Watch the short movies: futurevisionfound.org/2026-films #Vision #Retina #Ophthalmology #Blindness #Neuroscience #ScienceInnovation #VisionRestoration #EyeHealth #BiomedicalResearch

8/8. This work builds on inspiring studies showing that internal states shape spontaneous behavior over long timescales.🕜 Huge thanks to co-authors, institutions, and funders for making this possible! 🙏 @yourUMG @MPIforBI DFG @EKFStiftung @MBExC_de

7/8. In short: ~10 s before a spontaneous behavioral switch: ↑ decodability ↓ medial septum activity (and other regions) Our interpretation: internal drive gradually builds up, creating a transition-prone brain state that makes switching more likely.

1/8. Preprint!✨How spontaneous is spontaneous behavior?🧠🐭 We found that whole-brain fUSi signals predicted spontaneous behavior transitions seconds in advance. Inhibiting one node of this transition-prone state, the medial septum, facilitated switching! biorxiv.org/content/10.648…

Wait… localized norepinephrine transients in the awake visual cortex?! Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. nature.com/articles/s4159…

8/8 Last but not least: Jose Maria is looking for a postdoc in computational neuroscience 🧠💻 Don’t miss the chance to recruit him — he comes highly recommended! 🚀

7/8. In sum: arousal engages a brain-wide hemodynamic wave independent of noradrenergic tone! Huge thanks to all the coauthors, institutions (@yourUMG , @MPIforBI ), and funders (DFG, EKFZ, @MBExC_de) for making this possible! 🙏

1/8. New preprint! Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠. Surprisingly, this pattern was preserved during manipulations of the locus coeruleus, pointing to a minor role for noradrenaline. biorxiv.org/content/10.648…

Deadline extended for TENSS 2026 to March 15th!

@maxhodak_ @mardinly Congrats, @mardinly !

Some team updates at Science! My cofounder @mardinly has become Chief Scientific Officer Darius Shahida, an investor since the B, is joining full time to help turn our amazing technologies into an amazing business science.xyz/news/leadershi…