Epileptic Disorders

New findings shed light on managing complex epilepsy in AHC with ATP1A3 mutations — from drug choices to monitoring strategies and beyond. How can these insights change clinical practice? #Neurology onlinelibrary.wiley.com/doi/10.1002/ep…

This study shows how surface EMG can spot clonic seizures and set them apart from tremors doi.org/10.1002/epd2.7…

Can pulsatile corticosteroid therapy create lasting neurophysiological change in drug-resistant childhood epilepsy? doi.org/10.1002/epd2.7…

Ictal hypersalivation is more strongly linked to insular, opercular, and insulo-opercular seizures, while ictal spitting is a rare automatism associated with nondominant mesiotemporal onset. doi.org/10.1002/epd2.7…

Infant epilepsy insight: tailored MRI + ictal ASL hyperperfusion reveal FCD “hotspots,” guiding early surgery for better seizure control and outcomes onlinelibrary.wiley.com/doi/10.1002/ep…

Check out this interesting article "Features of cognitive dysfunction in late-onset temporal lobe epilepsy“ from Naoya Hasegawa et al. if you would like to learn more about the specific patterns of cognitive dysfunction. doi.org/10.1002/epd2.7…

Neonatal seizures ≠ always what they seem! ⚡ Video-EEG + EMG can spot vitamin-dependent epilepsy early, guiding treatment before genetics confirm it. Look for erratic myoclonus + epileptic spasms. onlinelibrary.wiley.com/doi/10.1002/ep…

Did you know eyelid myoclonia usually linked to other epilepsies can actually be the main seizure type in Lafora disease? These rare cases remind us why early genetic testing is key to uncovering hidden clues in epilepsy.onlinelibrary.wiley.com/doi/10.1002/ep…

doi.org/10.1002/epd2.7… Learn when to consider presurgical assessment, why early intervention matters, and how video-EEG, advanced imaging, neuropsychology, and invasive monitoring guide decision-making.

doi.org/10.1002/epd2.2… cortical dysplasias (FCDs) are developmental brain lesions caused by somatic or germline variants that dysregulate the mTOR pathway, while MOGHE arises from somatic SLC35A2 mutations affecting glycosylation

A practical guide to the updated seizure classification 2025 🔗[doi.org/10.1002/epd2.7… ] #Neurology #Epilepsy #ClinicalCase #MedEd #Seizureclassification

Seizures are described as with or without observable manifestations (basic) or by the chronological sequence of semiology (expanded). READ THIS INFORMATIVE PAPER. Click the link doi.org/10.1002/epd2.7…

Can you classify this seizure? Explore the 2025 ILAE practical guide featuring real-world cases and the latest updates in seizure taxonomy. doi.org/10.1002/epd2.7…

This practical guide aims to provide structured recommendations for clinicians to apply the updated 2025 ILAE seizure classification, thereby enhancing clarity, consistency, and clinical utility in epilepsy diagnosis and management. Click on the link onlinelibrary.wiley.com/doi/10.1002/ep…

Differentiating clonic seizures from tremors can be a major challenge in clinical settings, especially in the ICU where precise diagnosis is critical. Read this article for an interesting view doi.org/10.1002/epd2.7…

How would you classify this seizure? Find out the correct answer in this open-access practical guide, which includes this case as well (supplementary material S18) LINK : onlinelibrary.wiley.com/doi/epdf/10.10…

This systematic review & meta-analysis unpacks non-versive head deviation too giving Key insights for epilepsy surgery planning Read now: doi.org/10.1002/epd2.7… @SBeniczky @SHEIKHISMD @drdavidasish @IlaeWeb @Joanajribeiro

The practical guide to the updated seizure classification 2025 comprehensively explains how to approach seizure classification using the patient’s semiology and complementary tests. Learn clearly with the cited case videos - case : S10 doi.org/10.1002/epd2.7… @SBeniczky

Exciting opportunity for early-career epileptologists! The Epileptic Disorders (EPD) Internship Leadership Program is now accepting applications for Leader and Assistant Leader roles, starting July 1. @SheikhISMD @SBeniczky @drdavidasish @IlaeWeb

Anti-CASPR2 encephalitis on EEG many patients show (DSWA) and IED , reflecting widespread cortical dysfunction. Importantly, diffuse slowing and absence of deep (N3) sleep may signal a worse prognosis. CLICK THIS TO READ LINK onlinelibrary.wiley.com/doi/10.1002/ep…