Epigenetics News

MethylMetabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence.: Sadenosylmethionine SAM is the methyldonor substrate for DNA and histone methyltransferases that regulate epigenetic states and… bioportfol.io/RScsyq

BRD4 inhibition exerts antiviral activity through DNA damagedependent innate immune responses.: Chromatin dynamics regulated by epigenetic modification is crucial in genome stability and gene expression. Various epigenetic mechanisms have been identified… bioportfol.io/RScsyP

Promising New Approach to Attenuate Metastatic Disease in Mice: Epigenetic therapy which changes gene expression prevented some metastases. bioportfol.io/RSTKs7

Building Skills and Resources for Genomics Epigenetics and Bioinformatics Research for Africa Report of the Joint 11th Conference of the African Society of Human Genetics and 12th H3Africa Consortium 2018.: The 11th Congress of the African Society of… bioportfol.io/RSYQFY

Association of genetic and epigenetic variants in onecarbon metabolism gene with folate treatment response in hyperhomocysteinaemia.: Folate supplementation treatment is the firstline therapy in hyperhomocysteinaemia HHcy. Up to 40 of HHcy patients do… bioportfol.io/RSTzFp

The origin of genomic Nmethyldeoxyadenosine in mammalian cells.: The proposal that Nmethyldeoxyadenosine mdA acts as an epigenetic mark in mammals remains controversial. Using isotopic labeling coupled to ultrasensitive mass spectrometry we confirm the… bioportfol.io/RSTzF5

Interactions between metabolism and chromatin in plant models.: One of the fascinating aspects of epigenetic regulation is that it provides means to rapidly adapt to environmental change. This is particularly relevant in the plant kingdom where most… bioportfol.io/RSQkDc

All roads lead to Rome the many ways to pluripotency.: Cell pluripotency spatial restriction and development are spatially and temporally controlled by epigenetic regulatory mechanisms that occur without any permanent loss or alteration of genetic… bioportfol.io/RSMLzT

Association of genetic and epigenetic variants in onecarbon metabolism gene with folate treatment response in hyperhomocysteinaemia bioportfol.io/RSGvgV

Germline epigenetic inheritance Challenges and opportunities for linking human paternal experience with offspring biology and health.: Recently novel experimental approaches and molecular techniques have demonstrated that a male's experiences can be… bioportfol.io/RSK2WR

ATF7Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal LowProtein Diet.: Paternal dietary conditions may contribute to metabolic disorders in offspring. We have analyzed the role of the stressdependent epigenetic… bioportfol.io/RSK2W4

Transcriptional regulation of genes bearing intronic heterochromatin in the rice genome.: Intronic regions of eukaryotic genomes accumulate many Transposable Elements TEs. Intronic TEs often trigger the formation of transcriptionally repressive… bioportfol.io/RSC2NB

Distinct epigenomic and transcriptomic modifications associated with Wolbachiamediated asexuality.: Wolbachia are maternally transmitted intracellular bacteria that induce a range of pathogenic and fitnessaltering effects on insect and nematode hosts. In… bioportfol.io/RSC2M8

Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members.: Cytosine methylation is a ubiquitous modification in mammalian DNA generated and maintained by several… bioportfol.io/RSC2KW

Analysis of DNA methylation alterations in cellfree DNA fraction during colorectal cancer development.: During colorectal cancer CRC development in addition to genetic alterations several epigenetic changes including DNA methylation in the promoter… bioportfol.io/RS7Xxt

Like Heterochromatin Protein 1b represses fruit ripening via regulating the H3K27me3 levels in ripeningrelated genes in tomato.: Polycomb group PcG proteins play vital roles in plant development via epigenetically repressing the transcription of target… bioportfol.io/RS7XxX

Oxidative stress and epigenetics in obesity metabolic syndrome and olfactory perception. bioportfol.io/RS7XwY

Intraspecific and interspecific investigations of skeletal DNA methylation and femur morphology in primates.: Epigenetic mechanisms influence the development and maintenance of complex phenotypes and may also contribute to the evolution of… bioportfol.io/RRxNwR