Epigenomes MDPI

Our Issue 4 of Volume 9 has been released! On the cover: "Tripartite Interaction of Epigenetic Regulation, Brain Aging, and Neuroinflammation: Mechanistic Insights and Therapeutic Implications" by Prof. Nakashima, Dr. Nakashima et al. Browse the issue at mdpi.com/2075-4655/9/4

Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer Initiation mdpi.com/3779706 #mdpiepigenomes via @Epigenomes

Dr. Satoshi Kawaguchi and colleagues provide an integrated overview of miRNA-mediated regulation in chronic kidney disease, with particular emphasis on cell lineage functions within fibrotic pathways and disease-specific roles. Read their paper: mdpi.com/2075-4655/10/1…

Prof. Melanie Ehrlich and colleagues report some atypical epigenetic/transcription relationships for 92 genes that are highly and preferentially expressed in primary human myoblasts relative to heterologous cell cultures: mdpi.com/2075-4655/10/1…

Dr. Gwen Lomberk and colleagues model early mutant KRAS expression in non-cancerous pancreatic ductal epithelial cells to define the earliest molecular and structural responses to oncogenic signaling: mdpi.com/2075-4655/10/1…

Study by Dr. Orna Levran aimed to identify differential DNA CpG methylation that occurred in response to methadone maintenance treatment. You can read it at: mdpi.com/2075-4655/10/1…

Prof. Bachmann et al. analyzed CpG methylation of protein prenyltransferase genes 𝘍𝘕𝘛𝘈, 𝘍𝘕𝘛𝘉, 𝘗𝘎𝘎𝘛1𝘉, and 𝘙𝘈𝘉𝘎𝘎𝘛𝘈 to assess its role in PTase expression and gain deeper insight into the regulation of protein prenylation in cancer: mdpi.com/2075-4655/10/1…

🚀 Call for Sponsors — ncRNA2026 Conference🚀 Are you a pharma, biotech, or startup company developing innovative products in molecular biology, sequencing, or non-coding RNA research? shorturl.at/XxEcv We invite you to showcase your latest technologies at ncRNA2026: From Molecular Mechanisms to Clinical Impact📍 Leuven, Belgium | 🗓 24–26 June 2026. Join an audience of leading researchers, clinicians, and industry professionals and make your innovations visible to the community driving the future of RNA research. We would like to thank our current sponsors: Leuven Convention Bureau, @Non_Coding_RNA , @IJMS_MDPI , @Cells_MDPI , @diagnostic_mdpi , @Epigenomes , Biotech, Bioinformatics, Applied Biosciences, Biomed, Targets, @medsci_MDPI And our cooperators: @VirusesMDPI , Drugs & Drug Candidates, Current Oncology Your support makes this conference possible — we couldn’t do it without you! shorturl.at/XxEcv We look forward to seeing you at ncRNA2026. #ncRNA2026 #CallForSponsors #NonCodingRNA #RNAResearch #MolecularBiology #Genomics #Biotech #LifeSciences #TranslationalResearch

By systematically integrating multi-platform R-loop profiling datasets from mESCs, Prof. Dr. Kwonho Hong and colleagues identified a high-confidence set of conserved R-loop regions. Read their results at: mdpi.com/2075-4655/10/1…

🔬 [ncRNA2026] Abstract Submission Deadline Extended! shorturl.at/plP6B New Deadline: 24 March 2026 24–26 June 2026 | Leuven, Belgium Due to high demand, the abstract submission deadline for ncRNA2026 has been extended to 24 March 2026. Join leading researchers from around the world in Leuven to explore the latest advances in non-coding RNA research, including: • Fundamental molecular mechanisms • Clinical impact • Artificial Intelligence applications • ncRNA in medical, plant & bacterial systems 🎓 Chaired by Prof. Dr. George Calin, Prof. Dr. Manuela Ferracin, Prof. Dr. Eleonora Leucci, and Prof. Dr. Isidore Rigoutsos ✨ Confirmed invited speakers include: Janusz Bujnicki | Carlo Croce | Elisabetta Ferretti | Maite Huarte | Francesco Nicassio | Norbert Polacek | Panagiotis Roussos | Frank J. Slack | Igor Ulitsky 🎉 Organized by the MDPI open access journal Non-coding RNA in celebration of its 10th anniversary 📢 Submit your abstract for an oral presentation or poster:shorturl.at/plP6B We look forward to welcoming you to Leuven in June 2026! #ncRNA2026 #NonCodingRNA #RNAResearch #MolecularBiology #AIinBiology #LifeSciences #ConferenceAnnouncement

The Special Issue “Epigenetic Signatures in Metabolic Health and Cancer” is welcoming submissions until 30 April 2026! Join the 7 papers already published: mdpi.com/journal/epigen…

Varvara Maksimova, Dr. Kirill Kirsanov et al. aimed to evaluate the epigenetic activity of 40 drugs widely used in anticancer therapy using the HeLa TI cell-based assay. Read their paper at: mdpi.com/2075-4655/10/1…

Dr. Machado and Prof. Dr. Moretti reviewed insights into how chromatin is rewired by the major categories of pathogens during infection, highlighting case studies across infective agents and the functional consequences for immunity and cell fate: mdpi.com/2075-4655/10/1…

⏰ Last days to submit an abstract for #ncRNA2026! Dear #RNA lovers, the amazing lineup of conference chairs and international speakers for ncRNA2026: From Molecular Mechanisms to Clinical Impact (#Leuven, #Belgium | 24–26 June 2026) is set. The only thing missing is you and your findings! Secure your spot as an oral or poster presenter by submitting an abstract before 24 February 2026 at shorturl.at/VVOyV Don’t miss this opportunity to share your #RNAresearch, network, and gain visibility! #CallForAbstracts #NonCodingRNA #MolecularBiology #Genomics #Biotech #LifeSciences #TranslationalResearch

Study by Dr. David Martino et al. explores whether genome-wide blood DNA methylation changes were detectable in women with high versus low adherence to an Mediterranean diet throughout pregnancy. Read it at: mdpi.com/2075-4655/10/1…

Dr. Anastasia G. Volkova and colleagues aimed to evaluate the expression of HML-2 elements using RNA-sequencing data in samples from patients with colorectal cancer to identify patterns of the retrotransposons’ activity in different molecular subtypes: mdpi.com/2075-4655/10/1…

Review by Dr. Madalin-Codrut Coman, Monica Andreea Novac II et al. synthesizes knowledge on how chromatin remodeling, histone modifications, DNA methylation, and transcriptional regulation intersect with classical channelopathies and signaling pathways: mdpi.com/2075-4655/10/1…

In their pilot single-centre study, Dr. Manlio Vinciguerra and colleagues aimed to to assess whether circulating histone levels could be used for diagnostic purposes in patients with atrial fibrillation. Read their study at: mdpi.com/2075-4655/10/1…

Dr. Jaclyn M. Goodrich et al. evaluated epigenetic markers of toxicity in responding firefighters. They hypothesized that exposures from responding to train derailment would alter expression of microRNAs linked to carcinogenesis. Read their results at: mdpi.com/2075-4655/10/1…

Results by Dr. Patrick K. T. Shiu et al. demonstrate that an Hsp70 protein in Neurospora interacts with SMS-2 and mediates the silencing of unpaired genes. Read their study at: mdpi.com/2075-4655/10/1…

⏰RNA lovers, don’t miss the opportunity to submit an abstract before 24 February 2026! shorturl.at/YwoOB We are excited to announce ncRNA2026: From Molecular Mechanisms to Clinical Impact, taking place in Leuven, Belgium, from 24–26 June 2026. With outstanding conference chairs and a fantastic lineup of invited speakers, there’s just one thing missing — you and your research. 🧬 Conference sessions include: • Technological Advances in ncRNA Research • Clinical & Therapeutic Innovation • Emerging ncRNA Classes & Mechanisms • AI & ncRNA Discovery • ncRNA in Plants & Bacteria 📝 Submission details: Submission deadline: 24 February 2026 Abstract length: 150–300 words Presentation format: Oral, Poster, or Both Notification of acceptance: 24 March 2026 👉 Submit your abstract here: shorturl.at/YwoOB #CallForAbstracts #ncRNA2026 #AcademicOpportunity #ResearchImpact