Eswarappa Lab IISc

Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: doi.org/10.64898/2026.… Led by @emlekha @SaubhikSom @SandeepME_IISc Great collaboration with @anubhav_dhar @syncellbiolab @BICS_IISc @iiscbangalore

RNA India Meeting 2026 (RIM2026) will be held at IISc, Bangalore, from April 27-29, 2026. We are super excited to reveal the fantastic line-up of speakers. Registration deadline: March 31. Waiver request deadline-March 25. Look forward to welcoming the participants in Bangalore!

How short can a degron be? We report a 9–aa, genetically encoded, tunable degron that drives MDM2-dependent degradation and enables precise control of endogenous protein levels. Thanks to @EswarappaLab for the opportunity to explore this in yeast. #Degron #yeast #cellbiology

I will be presenting a poster on my doctoral work on In vivo Significance of Stop Codon Readthrough in MTCH2 from @EswarappaLab at EMBL Conference Protein Synthesis and Translational Control. Please drop by Poster #203 to know more about the work #EMBLProtein

IISc faculty Pradipta Biswas & Sandeep M Eswarappa were honoured by ISRO chairman Dr V Narayanan during the felicitation programme for Gaganyatri and Axiom-04 mission team, held in New Delhi on Thursday (Aug 21). @SandeepME_IISc

We welcome you all to the colloquium of Ms. Kirtana today. For details, please check below:

We invite you all to today's colloquium by @SaubhikSom. For details, please check poster :

Today, we invite you all to attend the colloquium by @DebrajManna27 , For details, please check below:

A moment of immense pleasure and honor to receive the prestigious Dr R K Maller Memorial Gold Medal for the best performance in coursework in the integrated PhD programme in Biological Sciences, from the honorable Chief Guest of the IISc Convocation 2025 Prof. Manjul Bhargava.

Today, we welcome you all to attend the symposium by @DebrajManna27 and Kirtana Vasu. For details, check below:

BICS invites everyone to attend today's symposium. For details, check below:

🎉Congratulations to @debrajmanna27 from @BICS_IISc @iiscbangalore, 🇮🇳, who was awarded an IUBMB Travel Fellowship to present his research at the #KSNCRNA25 meeting

Ever imagined your red blood cells fighting pathogens or transporting molecules other than gases? 🤔 Check out our latest review article @jbiolchem to learn more about the fascinating discoveries and "non-classical" functions of these cells. doi.org/10.1016/j.jbc.…

We enjoyed writing our latest review @jbiolchem on Emerging concepts in the molecular cell biology and functions of mammalian erythrocytes doi.org/10.1016/j.jbc.… Hope you have fun reading it too! @SangeethaDKumar @japi_17 @swatigh04639837 @SandeepME_IISc @iiscbangalore

Nobel laureate Venki Ramakrishnan visiting our lab. @EswarappaLab @NobelPrize

Congratulations to Swati Ghosh (@swatigh04639837), an Int PhD student in the lab, on being awarded the prestigious Hindustan Unilever Women in STEM Fellowship 2024 for her PhD work! 👩‍🔬 🎉 🎊 @iiscbangalore @HUL_News @BICS_IISc

IISc researchers show how the readthrough of a gene coding for FEM1B protein, plays a key role in the cell cycle, which has implications for cancer cell proliferation and tumour growth. iisc.ac.in/events/glitch-… #IIScresearch

.@nrakhtar3284, Sandeep M. Eswarappa and team @EswarappaLab uncover hominini-specific regulation of the cell cycle by stop codon readthrough of FEM1B #OpenAccess #ReadAndPublish journals.biologists.com/jcs/article/13…

I'm excited to share my First Person Interview article published in JCS, where I discuss the key findings, challenges, and motivations on our recent research titled "Hominini-specific regulation of the cell cycle by stop codon readthrough of FEM1B". @J_Cell_Sci @SandeepME_IISc