ExM

#Expansionmicroscopy helps see heat shock proteins (Timmerman, Baldwin, and Benesch labs, biorxiv.org/content/10.110…), the pathogen Chlamydia trachomatis (Rudel lab, frontiersin.org/articles/10.33…), and a Drosophila larva (Preibisch lab, nature.com/articles/s4159…). From the last paper:

Excited to highlight two #preprint 's for @preLights on developing trifunctional anchors for expansion microscopy (ExM)! Here's the link to the highlight: prelights.biologists.com/highlights/lab… and here are the preprints! biorxiv.org/content/10.110… biorxiv.org/content/10.110…

Congrats to the whole team of inventors on the patent for expansion microscopy technologies for the visualization of nucleic acids in cells and tissues, which was just granted, U.S. Patent 10364457! freepatentsonline.com/10364457.html

Differential expansion microscopy biorxiv.org/cgi/content/sh… #bioRxiv

Exciting to see the beginnings of #expansionmicroscopy of plant tissues! From the Nodine lab, Gregor Mendel Institute, biorxiv.org/content/10.110…:

It is amazing to see Tri-functional linkers for expansion microscopy in two recent preprints on July 1 biorxiv.org/content/10.110… (Huang and Seiple labs, UCSF @BoHuangLab @IanSeiple @XiaoyuShi2) and on July 8 biorxiv.org/content/10.110… (Hofkens lab, KULeuve @MarisaVanh @nedmcneelysson)

Evaluation of direct grafting strategies in Expansion Microscopy dlvr.it/R85vZ9

LR-ExM using tri-functional anchors enhances #expansionmicroscopy labeling efficiency to resolve molecular-scale features in cells. Work by @XiaoyuShi2 in collaboration with @IanSeiple lab. biorxiv.org/cgi/content/sh…

Pictures of clathrin coated pits (top, Seiple and Huang labs, UCSF, biorxiv.org/content/10.110…) and Drosophila amacrine neurons (bottom, Zinn lab, Caltech, biorxiv.org/content/10.110…), taken with the help of #expansionmicroscopy.

We plan to distribute some trifunctional anchors used in this work for free 😁, after official publication!! biorxiv.org/content/10.110… Let us know if you wanna try out this brighter, high labeling efficiency, 5-nm resolution LR-ExM. Easy to use! @IanSeiple

Excellent team.

Label-retention expansion microscopy disq.us/t/3g6ntnj

PEGylated liposome-encapsulated rhenium-188

Beauty in Biophysics 2019

#PLOSONE: Deformed alignment of super-resolution images for semi-flexible structures dx.plos.org/10.1371/journa…

Super-Resolution Microscopy Reveals That Disruption Of Ciliary Transition Zone Architecture Is A Cause Of Joubert… disq.us/t/2oqxt2e

Local Enrichment of HP1alpha at Telomeres Alters Their Structure and Regulation of Telomere Protection disq.us/t/34aqbj5

Deformed Alignment of Super-Resolution Images for Semi-flexible Structures in 3D disq.us/t/384fxp9

Deformed Alignment of Super-Resolution Images for Semi-flexible Structures in 3D disq.us/t/384fxp9