Francesco Fortarezza

#caseoftheday Tubular adenoma (a benign adnexal tumor) that, in this case, shows tubulo-cystic, papillary, eccrine, apocrine, and hydrocystoma-like features. In more than half of cases, the BRAF p.V600E mutation can be detected #pathology #dermpath #dermatology #PathX #MedX

A challenging case of a melanocytic lesion diagnosed as nevoid melanoma. Cytological atypia, mitotic activity, and loss of p16 expression supported the diagnosis. Interestingly, PRAME was negative #dermpath #pathology #dermatology #dermatopathology

“Nested-type” extramammary Paget disease. In other words, always perform immunohistochemistry to determine the origin of the cells (melanocytic, epithelial,etc.) when diagnosing intraepidermal lesions #pathology #dermpath #dermatopathology #dermatology #dermatologia #PathX #MedX

New paper - Bilateral Metachronous Typical and Atypical Carcinoid Tumors of the Lung - Busetto - 2025 - Thoracic Cancer - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/17… #pathology #lung #lungcancer

#WhatsNewInDermpath "Conceptual contextualization of neutrophilic dermatoses" by @ngelFernndezFl1 journals.lww.com/amjdermatopath… This article discusses neutrophilic dermatoses & describes the connection b/w neutrophilic dermatoses, autoinflammatory diseases, & autoimmune diseases.

#ClinicalPathologicChallenge 63F with known Darier disease (DD) presented to the ED after 1 week of fevers, gastroenteritis, and rapidly progressive skin blistering and desquamation. P/E: Diffuse epidermal sloughing with hemorrhagic crusting on the vermillion border

Collision tumor between a melanoma (on the left) and a seborrheic keratosis: a dangerous trap for dermoscopy that can hinder early diagnosis #pathology #dermpath #dermatopathology #dermatology #dermatologia #MedX #PathX

Happy Friday #dermpath! 😆🔬 Two of our articles were selected as Editor’s Choices in this month’s AJDP — and one even landed the front cover, featuring this photogenic gene schematic! 🧬🎨🎉 @AJDP_Journal @Coluchkaaaaa @rkenny168 #MDACCPath #molepath #pathology

Trichilemmoma: a benign follicular tumor with characteristic CD34 immunoreactivity. Multiple trichilemmomas may be associated with Cowden syndrome #pathology #dermpath #dermatology #PathX #MedX

Calcinosis cutis is a crippling sequela of dermatomyositis, likely driven by ongoing inflammation, ischemia, trauma, and specific autoantibodies. Notably, there is marked thickening of the basement membrane, typical of the disease #dermpath #pathology #dermatology #rheumatology

#caseoftheday: Meyerson dermatofibroma. The Meyerson phenomenon is not limited to nevi. These images show classic features of spongiotic dermatitis associated with a dermatofibroma. Some cases have been reported (PMID: 36345407) #pathology #dermpath #dermatology

Squamous metaplasia in sebaceous neoplasms can be a clue for microsatellite instability (consider possible Muir-Torre syndrome) #dermpath #pathology #dermatology #dermatopathology #MedX #PathX

Sin Anatomopatolologos no hay cáncer #pathology #patologia latercera.com/opinion/notici…

@MirunaPopescu13 Is the BRAF v600e (VE1) antibody

@FFortarezzaMD What is VE1? Never heard of it before 🤔

Undifferenziated/dedifferenziated melanoma: these tumors lack classical melanocytic markers and mimic sarcomas or carcinomas. Medical history and molecular profiling can guide the diagnosis #dermpath #pathology #dermatology #MedX #PathX #caseoftheday

@b_histopath Giemsa

@FFortarezzaMD What stain is this

Just a few Helicobacter pylori 😅 #Pathology #MedX #PathX #pathart

Microscopic anatomy and histology of a classic wood splinter in the thumb. Also useful for forensic colleagues working in wound ballistics😅 #dermpath #pathology #PathX #MedX #dermatology #dermatologia

@CakePath Yes:

@FFortarezzaMD Do you have low power? Uber-acute-gastritis?

Basal cell carcinoma with stromal amyloid deposition: a localized form of amyloidosis resulting from the degradation of keratins derived from tumor cells, as demonstrated by MNF116 (no systemic concerns!) #dermpath #pathology #histology #dermatology #PathX #MedX