Folding@home

🚨🚨🚨NEW SOFTWARE RELEASE!🚨🚨🚨 Help advance biomedical research by downloading/installing our new client software from foldingathome.org/start-folding/ This release has an improved UI and the option to control all the machines you have running Folding@home from a single webpage

Happy new year! 2024 was a productive year, and 2025 stands to be even more exciting! Our thanks to everyone who helped, and some reflections: foldingathome.org/2025/01/09/hap…

If you prefer the traditional approach, we also welcome tax-deductible gifts every.org/foldinghome-fo…

Too many requests for money this Giving Tuesday? Consider giving your spare CPU/GPU cycles to advance biomedical research instead! Download our software and join our community of citizen scientists here: foldingathome.org/start-folding/

Wow, cool to see that team Banana has overtaken "Default (No team specified)", closely followed by LinusTechTips! @bananocoin @LinusTech

We're making good progress on predicting properties of small molecules that are important determinants of whether they can be good drugs. Read more! foldingathome.org/2024/10/03/pre…

Want to do something meaningful with your computer? Contribute your computing power to Folding@home to accelerate biomedical research! foldingathome.org/start-folding/

Congratulations to Susanna @SusannaBar2 from Mitchell group @ChemistryUIUC and Song from @ShuklaGroup @ChBEIllinois for their work on understanding how enzymes tie the lasso knot in peptides published in Nature Chemical Biology @nchembio! igb.illinois.edu/article/resear…

Exciting new work on why the cryptic pockets that we've been hunting for exist foldingathome.org/2024/09/09/fun…

@DDurall3 Hmmm, shouldn't take that long. Can you please report this at foldingforum.org? That's where we do all our technical support.

@foldingathome How long should it take to download core? Been like this for 5.5 hours.

Now available open access! AlphaFold and Protein Folding: Not Dead Yet! The Frontier Is Conformational Ensembles annualreviews.org/content/journa…

Woohoo, our paper on the mechanism of a G protein inhibitor that is specific to one family of G proteins is out! Nice collab with the Blumer nad @AndreaSoranno labs pnas.org/doi/10.1073/pn…

Congrats to team AFGamers on jumping 691 positions on the leader board!

Its always fun to see how natural selection uses everything at its disposal, including rare protein structures that are hard to even detect. Even when this cryptic pocket is only open ~2% of the time, its still performing an important function.

This cryptic pocket has a function! The VP35 protein from Ebola virus performs multiple functions. We wanted to know if it toggles between different conformations that are responsible for different functions. It does! biorxiv.org/content/10.110…

Data organization is up to 17 milliseconds of simulations, taking 22 TB on disk, and still just getting started😀 #compchem @foldingathome

@danwat1234 @beatsinbrief We're reading up on the issue now to see where we can contribute. Thanks for the ping.

@beatsinbrief @foldingathome When are Monkeypox work units going to be generated??

🚨 BREAKING: The WHO declares a global emergency in response to the Monkeypox Virus outbreak.

Congrats to walterthurmond on jumping 855 positions on the leader board! Thanks walterthurmond for contributing!

Exciting to see our illustrious founder continuing to do great things!

2/ I recently joined the AI + @a16z podcast, to discuss this plus: * My work developing the @foldingathome, a distributed computing project to harness global computational power for biological research a16z.com/podcast/why-co…

@fconstantineau Thanks for contributing!

@foldingathome Eh, that’s me! Bought a new computer equipped with a Nvidia 4090 in june, my production is skyrocketing since.

Congrats to user Shogix for jumping 720 positions on the leader board! Thanks for all your work units!