Aaron Perez retweetledi

We've been told for decades that osteoarthritis is "wear and tear." But.... it's mostly wrong. If mechanical wear were the primary driver, runners would all need knee replacements. They don't. In fact, recreational runners have lower rates of knee OA than sedentary people. Most research shows that running can be protective. Go figure!
We've been told to rest. No... that's makes things worse. People who are active and strong keep their joints longer. No matter what the crays hsows.
One thing that's changed is metabolic health. Elevated blood sugar, insulin resistance, chronic low-grade inflammation — these degrade cartilage at a cellular level. Inflammatory mediators circulate through our bodies and affect joint tissue from the inside. I see this every day in my office… people (with solid metabolic health) with horrible-looking X-rays and very little pain, and people with mild arthritis on imaging who are miserable. The difference isn't the X-ray. It's the inflammation.
I put out an entire book on knee osteoarthritis on my substack lat summer.
So to answer the question… it hasn't always been like this. But our metabolic health hasn't always been like this either. And far too many people are not being given proper guidance on how to manage their OA.
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