The Dong Lab

Check out our new Account in Accounts of Chemical Research! We summarize our work on Pd/NBE-catalyzed vicinal difunctionalization of heteroarenes via double C–H activation—from catalyst design and mechanism to total synthesis. pubs.acs.org/doi/10.1021/ac…

Our work on NAHA-enabled carbonyl removal of cyclic ketones is now published in @J_A_C_S ! Congratulations to Zining! pubs.acs.org/doi/10.1021/ja…

@i_am_mangish @ChemRxiv @pengliu_group Thank you!

@GBD_Lab @ChemRxiv @pengliu_group Congratulations 👏🎉. Nice concept.

Check out our new preprint on @ChemRxiv with @pengliu_group! We developed an Ir-catalyzed, redox-neutral decarboxylative aromatization of carboxylated cyclohexanes. The carboxylic acid serves as a traceless anchor that enables good chemoselectivity. chemrxiv.org/doi/full/10.26…

@AmitBis89975104 @angew_chem Thank you!

@GBD_Lab @angew_chem Great work! Congratulations!

Check out our recent work on @angew_chem ! We developed a transition-metal-free “cut-and-sew” reaction that formally inserts five-membered heteroarynes into benzocyclobutenones, providing rapid access to fused heteropolycycles. Congrats to Cole! onlinelibrary.wiley.com/doi/epdf/10.10…

Last week, Sohee successfully defended her PhD—congratulations! From the total synthesis of harziane diterpenoids in Snyder group to exploring NAHA chemistry with us over the past two years, what an impressive scientific journey. Wishing her all the best in her next chapter!

Check out our recent work on @ChemRxiv : using our NAHA reagent, now we are able to remove the carbonyl group from cyclic ketones--through both reductive and annulative pathways! chemrxiv.org/doi/full/10.26…

Last week, several undergraduate students from our group completed their honors thesis defenses. Congratulations to Celeste, Justin, Melody, and Kayla on this milestone! We are so proud of your hard work and wish you all the best in your next chapter!

Check out our latest work on @J_A_C_S : a ligand-controlled enantioconvergent homologation enables efficient access to chiral tertiary alkyl boronates. Congratulations to @MiaoChen1997, @AnkiZXXu and Coco! pubs.acs.org/doi/10.1021/ja…

Last week, Cole successfully defended his PhD! He will be starting his postdoc at Northwestern University. Congratulations, Dr. Wagner! Wishing you all the best in the future!

Our recent work on aliphatic CO-to-N atom swap enabled by NAHA chemistry, now online in @ScienceMagazine ! Congratulations to Zining, Zhehan and @RongYehhh ! science.org/doi/10.1126/sc…

Check out our recent work on unstrained C–C activation! We report a site-selective C-demethylation of phenols and anilines enabled by a removable mono-directing group. Congrats to Yibin, @KaliusLY , Linda, and @CongjunY ! pubs.acs.org/doi/full/10.10…

By merging this method with carbonyl migration and established C–H oxidation chemistry, we are now able to apply nitrogen scanning in saturated systems!

Check out our recent work on aliphatic C-to-N atom swap enabled by NAHA chemistry! This strategy enables access to diverse saturated N-heterocycles from cyclic ketones or cyclic alkanes. See: chemrxiv.org/engage/chemrxi…

This weekend, we had a wonderful Christmas & New Year party with our group! Many thanks to Guangbin for hosting and bringing everyone together. Wishing the Dong group a joyful holiday season and a great year ahead!

Thrilled to see our recent Nature Chemistry work featured in @cenmag! Big thanks to Brianna Barbu for the great coverage! cen.acs.org/synthesis/shap…

Last Saturday, our PCE Center team joined the South Side Science Festival at UChicago — an inspiring day of outreach and community engagement! We shared ideas about sustainable chemistry and connected with the local community.

Meanwhile, we warmly welcome 2 new members, Byungjun Kim @Bjkim_Orgchem (postdoc) and Masanori Hirao (visiting scholar from Mitsui Chemicals) to the group! 🎉

Last week, we held a farewell party for our postdoc Yin Xu, who has made important contributions to C–H activation chemistry. He will soon start his independent career at Zhejiang University of Technology — we wish him all the best!