GPCRmd

New insights into the stepwise activation of β-arrestin are presented today at the GPCR Forum conference by Tomek Stepniewski! 👉 doi.org/10.1371/journa… Proud of this fantastic collaboration! 🙌

We’re ready to kick off Day 2 of the 2nd GPCR Forum Virtual Conference with the Australian, New Zealand and ECIs Sessions! After an exciting first day filled with insightful talks and vibrant discussions, we’re back with another full day of GPCR science!

🎙 Excited to see our team at the @GPCRForum Conference! 🧬 Tomek, Marta & Adrián will present in Session 4: ECIs of the GPCR Forum Community (12:00–13:20 CET). See you there! 🔗 #h.2rqhj5v80sr6" target="_blank" rel="nofollow noopener">gpcrforum.org/events/2nd-gpc… #GPCR #GPCRmd #StructuralBiology #MolecularDynamics

Join us as we dive into todays sessions featuring distinguished speakers from across the globe, sharing cutting-edge discoveries, novel methodologies, and fresh perspectives on GPCR biology, pharmacology, and drug discovery. Let’s continue the momentum and keep the conversation

🔥 Discover how structural dynamics drive signaling bias in GPCRs — a story presented today by Miguel Diéguez at the @GPCRForum Conference! 📅 Program: #h.r358qrwj9l1b" target="_blank" rel="nofollow noopener">gpcrforum.org/events/2nd-gpc… 🧬 From Nature Communications (2025): nature.com/articles/s4146… #GPCR #SignalingBias #MolecularDynamics

Exciting Announcement! 🎉 We’re thrilled to share that the 2nd GPCR Forum Virtual Conference 2025 will feature poster sessions at the end of each session across all three days, 12-14th November 2025!

D-1 to the 2nd GPCR Forum Virtual Conference! 🎉 We’re just one day away from an exciting three-day journey (📅 12–14 November) into the world of GPCR research and innovation!

🧠 New in Molecular Pharmacology: structurally similar 5-HT2A ligands, ketanserin and altanserin, show distinct G protein coupling patterns in human prefrontal cortex. 📄 Read: doi.org/10.1016/j.molp… #GPCR #5HT2A #Pharmacology #SignalingBias

🧬 New in PLOS Biology! A key arginine switch is revealed as the trigger for β-arrestin activation in CXCR7. Explore the full molecular dynamics simulations on GPCRmd. 📄 doi.org/10.1371/journa… #GPCR #MolecularDynamics #GPCRmd

🧬 New in PLOS Biology! We reveal how an arginine switch drives β-arrestin activation in CXCR7—full simulations on GPCRmd @t00mek88. 📄 Read: doi.org/10.1371/journa… 💾 Data: gpcrmd.org/dynadb/publica… #GPCR #StructuralBiology #MolecularDynamics #GPCRmd

📰 Excited to see our latest article nature.com/articles/s4146… featured in the news!🧬 Featured in: 🔹 La Vanguardia: lavanguardia.com/vida/20250716/… 🔹 Infosalus: infosalus.com/salud-investig… 🔹 El Punt Avui: elpuntavui.cat/societat/artic… #GPCR #DrugDiscovery #GPCRMDcommunity #ScienceNews

📰 Amino acids play a key role in how cells respond to drugs👇 grib.upf.edu/amino-acids-pl… the new study done by ,👩‍💻@GPCRmd of GRIB, coordinated by Dr. @JanaSelent @HMar_research @the_prbb

Excited to attend the 5th IRN i-GPCRnet Annual Meeting! 🧬 Hosted by @IQAC_CSIC & @UniBarcelona, it takes place at the Faculty of Pharmacy (UB), Barcelona, from July 7–9, 2025. Looking forward to great science and discussions! #iGPCRnet2025 #GPCR

Our latest work unravels how multiple intramolecular triggers shape preferential G protein coupling in CB2R 🧬 A step forward in precision drug design for GPCRs! Read here 👉 nature.com/articles/s4146… #GPCR #DrugDiscovery #MolecularDynamics #CB2R #GPCRMDcommunity

New study in Science Signaling shows how Gαs mutations linked to PHPIc disrupt GPCR signaling in a tissue- & mutation-specific way 🧬 MD data on @GPCRmd: 👉 gpcrmd.org/view/1296 & gpcrmd.org/view/1297 🔗 science.org/doi/10.1126/sc… #GPCR #MolecularDynamics #GPCRMDcommunity

🔬 Descubren nuevas vías a través de las que los medicamentos pueden modular las funciones de las células. 💊 Son puertas a las proteínas de la membrana celular que eran desconocidas y que son claves para el desarrollo de nuevos fármacos larazon.es/cataluna/descu…

Thanks to @larazon_es for covering our Nature Communications article! 📰✨ Our research uncovers new pathways for drug action on cells—paving the way for innovative therapies. 🔗 Read more: larazon.es/cataluna/descu… #DrugDiscovery #GPCR #MolecularDynamics #GPCRMDcommunity

📰 GRIB NEWS!📰 🔎New pathways discovered for #drugs to act on #cells @GPCRmd Unknow access points in cell membrane #proteins, enabling laboratory-developed drugs to modify cell function👀 Published by @NatureComms 👉grib.upf.edu/new-pathways-d…

Excited for the IRN i-GPCRnet Satellite Meeting 🇧🇷! 📍 2nd GPCR Signaling & Drug Discovery Symposium: 🎤 Marta López Balastegui (Day 1 - 12:15) 🎤 Jana Selent (Day 2 - 14:30) Info 👉 sites.google.com/view/usp-igpcr… #GPCR #DrugDiscovery #GPCRMDcommunity

🔬 The 2nd round of GPCRmd data is out! Covering 60% of GPCR structures, it reveals allosteric sites & lateral gateways into the receptor core. 🔗 Read: doi.org/10.1038/s41467… #GPCR #GPCRmd #MolecularDynamics Explore it with our new tools: #tools" target="_blank" rel="nofollow noopener">gpcrmd.org/#tools