ChristianaCare Gene Editing Institute

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ChristianaCare Gene Editing Institute

ChristianaCare Gene Editing Institute

@GeneEditingDE

Worldwide leader in #GeneEditing/#CRISPR. The first gene editing research institute based in a community cancer center, @ChristianaCare. Partners: @TheWistar.

Newark, DE Katılım Nisan 2018
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ChristianaCare Gene Editing Institute
Nothing's scary about CRISPR, but there's something spooky about our scientists today! We're enjoying the holiday by dressing up. To all the trick-or-treaters and celebrators of the day: go 'bananas' tonight, but don't go too crazy on the candy - maybe just a 'bite'!
ChristianaCare Gene Editing Institute tweet mediaChristianaCare Gene Editing Institute tweet media
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ChristianaCare Gene Editing Institute retweetledi
CRISPR Medicine
CRISPR Medicine@CrisprMedicine·
𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐑𝐞𝐩𝐨𝐫𝐭 𝐍𝐞𝐰 𝐒𝐭𝐫𝐚𝐭𝐞𝐠𝐲 𝐭𝐨 𝐄𝐧𝐡𝐚𝐧𝐜𝐞 𝐂𝐑𝐈𝐒𝐏𝐑–𝐂𝐚𝐬9-𝐌𝐞𝐝𝐢𝐚𝐭𝐞𝐝 𝐇𝐨𝐦𝐨𝐥𝐨𝐠𝐨𝐮𝐬 𝐑𝐞𝐜𝐨𝐦𝐛𝐢𝐧𝐚𝐭𝐢𝐨𝐧 In a hunt for ways to improve the efficiency of CRISPR–Cas9-mediated homologous recombination, researchers at ETH Zürich and Memorial Sloan Kettering Cancer Center find that a single exonuclease, TREX1, reduces HDR efficiency when the repair template is a single-stranded or linearised double-stranded DNA. TREX1 knockout improved HDR efficiency, indicating new avenues for increasing CRISPR-Cas9-mediated HDR in TREX1-expressing contexts. The study was led by Jacob Corn at ETH Zürich. crisprmedicinenews.com/news/researche… #crisprmedicinenews #crisprmedicine #crisprcas9 #fanconianemia #geneediting
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ChristianaCare Gene Editing Institute
In this study, the first example of heritable gene editing in the entire phylum of Tardigrada was researched, evaluated, and deemed a success. This foray into the world of 'water bears' could have major implications for human genome editing in the future. journals.plos.org/plosgenetics/a…
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