One Health Genomics Edinburgh

New Publication: Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance @EdinUni_IGC @EdinUniNeuro nature.com/articles/s4146…

New Publication: Organisation and dynamics of individual DNA segments in topologically complex genomes @EdinUni_IGC academic.oup.com/nar/article/53…

New Publication: Review: Assessing available genetic diversity estimates of rare breeds of livestock @roslininstitute @TheDickVet #kg005" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

New Publication: Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development @EdinUni_IGC @Hannah_K_Long @uttley_kirsty journals.biologists.com/dev/article/15…

New Publication: Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma @EdinUni_IGC febs.onlinelibrary.wiley.com/doi/10.1002/18…

#GettingGenomeMe Genomics Researcher Profile Dr James Furniss is a Facility Manager at Roslin Institute and here he talks about his work in the Genomics Platform Core Facility @roslininstitute onehealthgenomics.ed.ac.uk/james-furniss

New Publication: Clinical implications of bone marrow adiposity identified by phenome-wide association and Mendelian randomization in the UK Biobank @EdinUniUsher @EdinUniImaging @EdinUni_IGC @EdinUniNeuro @WillCawthorn nature.com/articles/s4146…

New Publication: Accurate prediction of gene deletion phenotypes with Flux Cone Learning @SBSatEd @CharlotteMerzb1 @doyarzunrod nature.com/articles/s4146…

New Publication: Semiparametric efficient estimation of small genetic effects in large-scale population cohorts @EdinUni_IRR @EdinUni_IGC @EdinUniMaths @AvaKhamseh academic.oup.com/biostatistics/…

New Publication: The loss of microRNA-26b promotes aortic calcification through the regulation of cell-specific target genes @ColSciEng @EdinUni_IGC @caporalilab #singlecelltranscriptomics #aorticdisease #microRNAs academic.oup.com/cardiovascres/…

New Publication: Limited overlap between genetic effects on disease susceptibility and disease survival @EdinUni_IGC nature.com/articles/s4158…

New Publication: Structural variant landscape provides insights into genome organisation and domestication in European seabass @roslininstitute @TheDickVet bmcbiol.biomedcentral.com/articles/10.11…

New publication: A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison @EdinUni_IGC @roslininstitute @EdinUniLBC nature.com/articles/s4422…

New Publication: Integrating cross-sample and cross-modal data for spatial transcriptomics and metabolomics with SpatialMETA @BMTOeduni nature.com/articles/s4146…

New Publication: The commercial roots of the genomic commons @UoEresearchSSPS journals.sagepub.com/doi/10.1177/03…

Today is One Health Day! #OneHealth Find out more from the One Health Commission onehealthcommission.org/en/events_sinc…

New Publication: Genome-Wide Aggregated Trans Effects Analysis for Circulating Proteins Indicates a Key Role of Immune Checkpoints in Type 1 Diabetes @EdinUni_IGC @EdinUniUsher diabetesjournals.org/diabetes/artic…

Edinburgh Next Generation of Genomics Symposium #ENGoGS2025 Join us on 17th November at the Playfair Library to hear from Early Career Researchers working across disciplines in genetics and genomics. Link below for details and registration. onehealthgenomics.ed.ac.uk/ENGoGS25

New Publication: Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery @SchoolofPPLS @hayley_s_m nature.com/articles/s4139…

New Publication: Assessing variant effect predictors and disease mechanisms in intrinsically disordered proteins @EdinUni_IGC @jmarshlab journals.plos.org/ploscompbiol/a…