Gord Fishell

Excited for the publication of our recent work on how pyramidal cells shape the identity of interneurons in the Cortex! Big shout out to @artofbiology and Sherry Jingjing wu! nature.com/articles/s4158…

Thoughts on Anthropic and the pentagon....The US military has 3000 strikes in Iran, all determined using Claude's help -assume 94% accuracy and 0 hallucinations. So 180 errors in targeting. How many civilians are killed in those errors? That is why we can't autonomize warfare!

Chandelier baby… Now you're talking! Well done, Ethan!!

Excited to be on the organization meeting for the 6th annual NCM conference on Neural Circuits in Health & Disease. Terrific line up of speakers!

Pay attention to the amazing tool set that Min has assembled! Central in the analysis of our recent Nature work! nature.com/articles/s4158…

@akaye @koen_vervaeke If you want to test the enhancers we published in Neuron, go ahead and try them. All available at Addgene.

@koen_vervaeke @JDimidschstein @GordFishell Really curious to see the answer to this!

What’s the latest on viral methods for targeting somatostatin and VIP neurons in a mouse-line-independent manner. Anything tried and tested? @JDimidschstein @GordFishell

@koen_vervaeke If you want to test the enhancers we published in Neuron, go ahead and try them. All available at Addgene.

Thrilled to see our PNAS paper featured in @GiacomoI commentary. A fantastic recognition of how biologically grounded cortical microcircuits can accelerate the next generation of NeuroAI—and a meaningful step connecting it to neuroscience pnas.org/doi/10.1073/pn…

Excited to share our new preprint! LARIS enables accurate and efficient ligand and receptor interaction analysis in spatial transcriptomics biorxiv.org/content/10.110… Joint work from Fishell lab @GordFishell and Fei Chen lab @insitubiology @sundakao at the Broad @broadinstitute 1/n

Excited to report the publication of LARIS, a program that can predict spatiotranscriptic LIgand-Receptor interactions. This work was led by @artofbiology (Min Dai in my lab) with Fei Chen's lab at the Broad. biorxiv.org/content/10.110…

And now the Neuromorphic piece has been picked up a one of the 10 most notable AI papers this week! Exciting! Well done Suraj!! aiworld.eu/story/this-wee…

Well to complement my son's efforts here is some background into my own first foray into neuromorphic computing. The original article can be seen in PNAS! A big shout out to Suraj Honnuraiah, who made it all happen!. growkudos.com/publications/1…

Well when it rains it pours. My son Will @fishell_will , just published a paper on biorxiv, much closer to my heart with my lab member Suraj Honnuraiah on spiking neural networks and understanding why they struggle as LLMs. biorxiv.org/content/10.110…

In a whimsical review of his arXiv.org paper, my son Will discusses the use of TempoBench in evaluating LLMs. I particularly enjoyed the faux ad for the TempoBench "product". You go Will! wfishell.github.io/landing.html

Really excited to see my son Will @fishell_will publish his first work Tempobench that measures temporal causality and reasoning in LLMs. arxiv.org/abs/2510.27544

Updated how pyramidal neurons impact specific interneuron subtypes. Turns out spontaneous activity, Wnt signaling in Parvalbumin Interneurons and integrin-signaling in Somatostatin neurons are the culprits! Also see how optimal transport tracks identity.biorxiv.org/content/10.110…

Outside my usual comfort zone. This is the amazing work of Dionnet Bhatti a graduate student who examined the defensive behavior mediated lateral septum through careful SC analysis of the CRHR2 populations. Dionnet is someone you should keep your eyes on! researchsquare.com/article/rs-683…

At my last year of attending the McKnight conference. Such an amazing group of scientists. A big shout out to Lauren Orefice @lauren_orefice who gave an amazing talk this morning!

Here is a chat with Bosilijka Tasic and myself about the enhancer-mediated AAVs that we were both centrally involved in publishing. I truly believe these approaches are fundamentally important for both basic and clinical approaches! braininitiative.nih.gov/news-events/bl…

New Neuron issue! Discover methods for accessing neuronal and non-neuronal cell types in the CNS from the BRAIN Armamentarium Consortium 🧠🔧 Read insights from Bosiljka Tasic & @GordFishell: cell.com/neuron/fulltex… Explore the full issue here: cell.com/neuron/current