Griffin Barnes

Optimized Biomimetic Syntheses of Discorhabdin B and Aleutianamine Drives a Deeper Exploration of Their Anticancer Potential | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

Electrochemistry Goes Mainstream: Applications in Modern Total Synthesis, a review appearing today in @ChemRxiv :chemrxiv.org/doi/full/10.26…

Out now in @angew_chem : onlinelibrary.wiley.com/doi/abs/10.100…

3D degraders, enabled by redox-neutral radical cross-coupling, appearing today in @ChemRxiv : chemrxiv.org/doi/full/10.26…. A fabulous collaboration with BMS and the Parker lab.

Hey @support can you please reactivate our lab account @baranlabreads? All we do is post our science there

Final version appeared today in @angew_chem : onlinelibrary.wiley.com/doi/10.1002/an…

Radical Retrosynthesis of Natural Products Enabled by Iron-based Reductive Olefin Coupling. Published today in @ChemRxiv : chemrxiv.org/engage/chemrxi…

Terpenoid Synthesis via Convergent Radical Annulation! Appearing in @ChemRxiv today: chemrxiv.org/engage/chemrxi…

TEN STEPS TO A MARINE TREASURE: Gram-Scale Synthesis of Bipinnatin J – featuring methods that weren't known ≅3 years ago to forge 3 key C–C bonds... Appearing today in @ChemRxiv (chemrxiv.org/engage/chemrxi…). Quick Summary: A concise, scalable total synthesis of (–)-Bipinnatin J is disclosed. Commencing from inexpensive starting materials, this marine diterpenoid was fashioned through a highly convergent synthesis enabled by two Ni-electrocatalytic decarboxylative cross–couplings (DCC) leveraging succinate as an ethylene 2-carbon bridge, a unique halogen dance- Zweifel sequence to rapidly access a trisubstituted furan, a recently disclosed Ni-catalyzed 1,6-conjugate addition, and an asymmetric proton transfer. Shout out to the team that made it happen: @tonyjohn07 @griffin__barnes @maithiliterpene

Hydrogen-Atom-Transfer-Initiated Radical/Polar Crossover Annulation Cascade for Expedient Access to Complex Tetralins (Christopher D. Vanderwal and co-workers) @thevanderwallab @_lkjohnso #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents | Journal of the American Chemical Society @UCIrvine @TotalSynthesis @TotalSyntheses #Divergent #Synthesis #Pyrroloiminoquinone #Alkoids #Antiprotozoal pubs.acs.org/doi/10.1021/ja…

A #Synthesis of Alstonlarsine A via Alstolucines B & F Demonstrates the Chemical Feasibility of a Proposed Biogenesis by @Griffin__Barnes, Allen Hong, and Christopher Vanderwal @thevanderwallab at @UCIChemistry in @angew_chem onlinelibrary.wiley.com/doi/10.1002/an…

If you then you don't don't love deserve me at my me at my

@AidBot2QJ7 you MUST have aced your physics test this morning

In 2016: 70% of 18-29-year-olds DID NOT vote 60% of 30-44-year-olds DID NOT vote Only 38% of 45-64-year-olds did not vote & just 15% of 65+ did not vote There is a reason America isn't progressing. It’s because the people who care about progress don’t care about voting VOTE!!

Congratulations (?) to the owner of the one bracket out of 17.3 million who has gone 0 for 20 so far in Tournament Challenge.

RESPECT. US.

Grayson being Grayson.