Harrison Besser

To improve the diagnosis and monitoring of celiac disease — and to find pathways for treatment — longtime collaborators are testing the use of a fluorescent compound to track and illuminate a celiac disease-triggering molecule in patients. stan.md/42HVrk3

Gita Abhiraman, graduating from the Stanford School of Medicine, was inspired to pursue a career in immunotherapy after an early treatment saved her mother’s life. Now, she’s focused on advancing treatments that improve patient outcomes. #StanfordMed2025 med.stanford.edu/news/insights/…

Excited to share this work from the Garcia Lab out today in @NatureComms! We engineer "cytokine adaptors", molecular switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS

Excited to share a review I recently wrote with my advisor, Chaitan Khosla (@KhoslaLab @Stanford_ChEMH), about the molecular basis of celiac disease and how teams of translational scientists and clinicians are seeking to treat it! doi.org/10.1016/j.tips…

@StevenTangPhD @YaleMBB Congratulations Steven!

Delighted to share that I am joining Yale's faculty in @YaleMBB Molecular Biophysics and Biochemistry. My lab studies how the cell-surface proteome shapes and sculpts cellular membranes in regenerative physiology and infectious disease. Learn more at: steventanglab.com

Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP-1 Pathway | Journal of the American Chemical Society ⁦@Stanford_ChEMH @Stanford @StanfordUChem #Lysosomal #LYTAC #Degradation #CellSurface #Proteins #LRPPathway ⁩ pubs.acs.org/doi/10.1021/ja…

A structural blueprint for interleukin-21 signal modulation dlvr.it/SqymnY

Better late than never! Happy to share this work alongside my co-authors including @StevenTangPhD @grahamserwin out now @JBC. Initially, we were interested in studying the gp41 pocket of HIV-1, a highly conserved drug/vaccine target..🧵(1/5) doi.org/10.1016/j.jbc.…

Online now! LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens dlvr.it/SgQx9w #chembiol