RudolfHoermann

Some of you may be interested that our new thyroid book has been released online, hard copy will also be available soon. link.springer.com/book/10.1007/9…

Sadly, John Midgley, a pioneer in #thyroid diagnostics and co-author of multiple papers by our group, passed away. Read Rudolf Hoermann's (@HoermannRudolf ) obituary at The Guardian: theguardian.com/society/2024/a…

An interview about perspectives in endocrinology endocrinenews.endocrine.org/a-second-opini…

Systems biology of #thyroid_homeostasis: Relational stability of two intertwined feedback loops protects #FT3 concentration despite variations in #thyroid's secretory capacity. doi.org/10.1177/204201…

In physiology, it is all about homeostasis. Investigating the control system of the hypothalamic-pituitary-thyroid axis including FT3, the biologically more active but often neglected thyroid hormone. frontiersin.org/articles/10.33…

What is subclinical #hypothyroidism? Is it a true disease or a mere laboratory constellation? What we need is a more clinically inclusive definition for subclinical #thyroid disease, more deserving of this name. pubmed.ncbi.nlm.nih.gov/34243143/ doi.org/10.1530/eje-20…

The Student-t distribution was developed at the Guinness Brewing Company. johndcook.com/blog/2008/06/2…

@Stofskiftesygdo Far from providing a universal answer by itself, considering its conditional #control function and adaptive relationship with thyroid hormones, interpretation of #TSH requires reconciliation and complementation by #thyroid #hormones in various conditions. pubmed.ncbi.nlm.nih.gov/32854594/

Tweetorial on our new paper, part 1: #Thyrotropin (#TSH) concentration is elevated in post-traumatic stress disorder (#PTSD), reflecting an elevated #setpoint of #pituitary-#thyroid feedback control. doi.org/10.3389/fendo.…

It is about more than central tendency: Choosing Between #Parametric and Non-Parametric Tests: A Response pubmed.ncbi.nlm.nih.gov/32621583/

The fifth hyperfactorial: 5⁵ × 4⁴ × 3³ × 2² × 1¹ = 86400000 milliseconds is exactly 1 day!

#Thyroid homeostasis is a non-ergodic system. Individual factors are from paramount importance in substitution therapy with #levothyroxine, raising problems in substituting one #LT4 preparation with another one. ncbi.nlm.nih.gov/pubmed/3223691… doi.org/10.1007/s40262…

Good call.

likewise

We see the thyroid gland at the fore front of the defence against the challenge of capacity reduction, with TSH efficiently controlling the glandular hormone depots.

Simpson's paradox: An important, but underrecognized phenomenon in #thyroid function: doi.org/10.1186/s12902…

This is an excellent animation of Simpson's paradox:

Functional and Symptomatic Individuality in the Response to #Levothyroxine Treatment - an important fact to be considered. frontiersin.org/article/10.338… doi.org/10.3389/fendo.…

Should you care about ergodicity, even if you may not know what this is? Reviewing LT4-treatment for hypothyroidism doi.org/10.7573/dic.21…

Is it time to reassess the treatment of hypothyroidism? We think so, doi.org/10.1186/s12902…