Holly Addison

25 posts

Holly Addison

Holly Addison

@HollyGAddison

PhD student at MPI Marburg @mpi_marburg🕺 Interested in electron transfer proteins @Rebeleinlab

Germany Katılım Ağustos 2021
53 Takip Edilen83 Takipçiler
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Holly Addison
Holly Addison@HollyGAddison·
I am excited to share that my first research paper is now available online at @mBio: doi.org/10.1128/mbio.0…. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).
Max Planck Institute for Terrestrial Microbiology@mpi_marburg

Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: mpi-marburg.mpg.de/1361203/2024-0…

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Antonio J. Pierik
Antonio J. Pierik@AJPierik·
Dear nitrogenase lovers: have a look at our BioRxiv prepublication. Ana Maciel, Jessica Soares, ..., Antonio Pierik and Johannes Rebelein proudly present that Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. doi.org/10.1101/2024.1…
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Holly Addison
Holly Addison@HollyGAddison·
I am excited to share that my first research paper is now available online at @mBio: doi.org/10.1128/mbio.0…. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).
Max Planck Institute for Terrestrial Microbiology@mpi_marburg

Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: mpi-marburg.mpg.de/1361203/2024-0…

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Holly Addison
Holly Addison@HollyGAddison·
@mbio I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab!
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Holly Addison
Holly Addison@HollyGAddison·
@mbio Both Fds are excellent targets for bioengineering the e- flux to the Fe-N2ase with aims to further increase the conversion of N2to NH3.
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Holly Addison
Holly Addison@HollyGAddison·
@mbio We found that 2 distinct Fds with different redox centres are essential for N2-fixation by the Fe-N2ase, though surprisingly, our results suggest the 2 Fds likely have separate roles in N2-fixation.
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Holly Addison
Holly Addison@HollyGAddison·
@mbio We investigate the unknown e- transfer to the Fe-N2ase and tackle the question whether Fds are specific or redundant in the e- transport to the Fe-N2ase in Rhodobacter capsulatus.
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Holly Addison
Holly Addison@HollyGAddison·
Finally, I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab. Thanks for reading 😀
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Holly Addison
Holly Addison@HollyGAddison·
In conclusion, we established that 2 distinct Fds with different redox centres are essential for Fe-N2ase mediated N2-fixation. These Fds are excellent targets for bioengineering aiming to further increase the conversion of N2 to NH3and CO2 to hydrocarbons by the Fe-N2ase.
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Keşfet

@AJPierik @RebeleinLab @ChemEurJ @miCHRIScopy @uniwue @mbio @bobelly_ @mbiojournal