INCEPT

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INCEPT

INCEPT

@INCEPTdk

INCEPT: The Intensive Care Platform Trial research programme. Profile no longer active, updates on website: https://t.co/hesjeYJUCu

Copenhagen, Denmark Katılım Nisan 2021
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INCEPT
INCEPT@INCEPTdk·
The Intensive Care Platform Trial (INCEPT) research programme aims to prepare, initiate and run an adaptive platform trial assessing commonly used interventions in acutely ill intensive care unit (ICU) patients. Follow this account and incept.dk for updates!
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Anders Granholm
Anders Granholm@andersgranholm·
adaptr #rstats package for simulating complex adaptive trials with adaptive stopping, arm dropping, and randomisation updated to v.1.40 - link and details below. @INCEPTdk
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Anders Granholm
Anders Granholm@andersgranholm·
New version of our 'adaptr' R package on CRAN including important new functionality (trial calibration) and other improvements - see inceptdk.github.io/adaptr/ and thread below if you're interested in simulation of complex adaptive trial designs. 1/..
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Anders Granholm
Anders Granholm@andersgranholm·
Are days alive without life support/out of hospital (DAWOLS/DAOOH) associated with longer-term health-related quality of life (HRQoL)? We aimed to find out - new article online (OA), doi.org/10.1111/aas.14…, conducted as part of the @INCEPTdk programme. 1/..
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Anders Granholm
Anders Granholm@andersgranholm·
Now online in @JClinEpi (OA): jclinepi.com/article/S0895-… In this manuscript we provide an overview of the key methodological considerations for (multi-arm, multi-stage) clinical trials using adaptive stopping, arm dropping, and randomisation with a worked example. Details below 1/
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Anders Granholm
Anders Granholm@andersgranholm·
New paper in @CritCareMed: to inform selection and handling of patient-important outcomes other than mortality in @INCEPTdk, we conducted a scoping review summarising selection, definition, and handling of these outcomes in contemporary ICU trials (1/..) doi.org/10.1097/ccm.00…
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Anders Granholm
Anders Granholm@andersgranholm·
Minor update to the 'adaptr' R package for adaptive trial simulation now available on CRAN (cran.r-project.org/web/packages/a…). Details on the package available below and on inceptdk.github.io/adaptr/. @INCEPTdk @benskov @LangeTheis
Anders Granholm@andersgranholm

We have a paper on our 'adaptr' R-package for adaptive trial simulation and comparison (developed as part of the @INCEPTdk project) published in @JOSS_TheOJ joss.theoj.org/papers/10.2110…. The package is documented on a stand-alone website at inceptdk.github.io/adaptr/. (1/6)

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INCEPT
INCEPT@INCEPTdk·
This week, the INCEPT programme received the ‘Innovation of the year’-award in the first Danish awards ceremony for clinical trials. We are proud and highly motivated to continue our work on establishing the INCEPT platform trial! Coverage (in Danish): dagensmedicin.dk/syv-glade-vind…
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JOSS
JOSS@JOSS_TheOJ·
Just published in JOSS: '`adaptr`: an R package for simulating and comparing adaptive clinical trials' doi.org/10.21105/joss.…
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Anders Granholm
Anders Granholm@andersgranholm·
adaptr: Adaptive Trial Simulator - new #rstats package for simulating adaptive trials: inceptdk.github.io/adaptr/ Simulates/compares trial designs using adaptive stopping, arm dropping and randomisation. Developed as part of the @INCEPTdk project. Details below: (1/6)
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