Isa Lucet

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Isa Lucet

Isa Lucet

@Isa_Lucet

Lab Head Chemical Biology @WEHI_research | Structural Biologist shedding invisible 🫥 light on (Pseudo)Kinases|Drug Discovery | Promoting STEM Leadership

Australia, Melbourne Katılım Eylül 2021
181 Takip Edilen261 Takipçiler
Isa Lucet
Isa Lucet@Isa_Lucet·
Absolutely thrilled to see ProteinDJ released. Many thanks to @joshuamhardy Dylan Silke and the team Junqi Pan, Andrew Thompson, Julie Iskander, @TonyPapenfuss for their enormous amount of work, making this pipeline open source.
Josh Hardy@joshuamhardy

I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.0…

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Isa Lucet
Isa Lucet@Isa_Lucet·
@ONJCRI @scisignal @latrobe Excited to see this DCLK1 study published, a collaborative work @latrobe with Michael Buchert and team that started many years ago, reinforcing our efforts in developing @WEHI_research, @Isa_Lucet, bespoke DCLK1-based diagnostics &therapeutics. Congratulations to all.
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ONJ Cancer Research Institute
ONJ Cancer Research Institute@ONJCRI·
💫 Our new publication in @scisignal reveals insights into gastric cancer progression! Funded by @latrobe, Dr Shoukat Sterle & team found inhibiting DCLK1 reduces tumour growth and prevents cancer from reshaping its environment. Congrats to the team! 👉 tinyurl.com/onjsho
ONJ Cancer Research Institute tweet mediaONJ Cancer Research Institute tweet media
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James Murphy
James Murphy@pseudokinase·
Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last nature.com/articles/s4200… Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me
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Isa Lucet
Isa Lucet@Isa_Lucet·
Many thanks to @KRogers1001 and her team @geogphotog Mike M, Lacklan W and to @DebnathGhosal and Andrew Leis for their dedicated support and to all others. Thanks to @nhmrc , Melbourne Research Scholarship and @WEHI_research for funding.
James Murphy@pseudokinase

Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last nature.com/articles/s4200… Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me

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Isa Lucet
Isa Lucet@Isa_Lucet·
Thrilled about our latest Pseudokinase research published today in @CommsBio, showing EphB6 power in promoting cell cell adhesion through formation of intercellular tubes. Many congratulations to our star PhD student @LungYu_Liang.
James Murphy@pseudokinase

Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last nature.com/articles/s4200… Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me

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Charles Bayly-Jones
Charles Bayly-Jones@bj_charles·
@joshuamhardy hey mate, I enjoyed your talk. TEMPO is a taking off! A really great initiative. If we can, Monash should contribute more material or content, whatever helps. Keep it up 🤘
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ARC CCeMMP
ARC CCeMMP@CCeMMP·
@CCeMMP group photo of centre members/affiliates at #cryoz23 - a great turn out in Brisbane! And thanks to outreach committee members for coordinating our 'macromolecular' assembly photoshoot 😀 @arc_gov_au #croEM #croET (credits to @LouBrillault for the photo).
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Josh Hardy
Josh Hardy@joshuamhardy·
ARC CCeMMP members enjoying a lunch break during the CRYOZ23 cryo-EM workshops. We've been learning cryo-electron tomography, modelling, and image analysis. @CCeMMP @UQ_SCMB
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The Florey
The Florey@TheFlorey·
Calling scientists and chemists in Melbourne 🧑‍🔬 Coming all the way from Copenhagen, Prof Meldal will *next week* present his Nobel Prize-winning work in 'click chemistry' work to the scientific community in Parkville 🧪 Register your attendance here: bit.ly/ProfMortenMeld…
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Isa Lucet
Isa Lucet@Isa_Lucet·
@purton_louise @pseudokinase @dr_opatel Let’s also hope for a cultural shift in Australia’s academia-industry funding landscape, enabling a better recognition of academic researchers dedicating their research towards advancing the discovery of therapeutic drugs!
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James Murphy
James Murphy@pseudokinase·
Big congrats to Prof @Isa_Lucet and @dr_opatel Huge achievement. I’ll be raising a glass to you. This is a long game and folks out there assessing grants should take notice that drug discovery is about base hits, not home runs
WEHI (Walter and Eliza Hall Institute)@WEHI_research

A fantastic achievement for a home-grown Australian discovery. Congrats to WEHI #structuralbiologists, @Isa_Lucet @dr_opatel for their contribution to structure-based #drugdiscovery of #momelotinib during their time at @MonashUni in partnership with Cytopia. #WomenInScience

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Isa Lucet
Isa Lucet@Isa_Lucet·
@dr_opatel @pseudokinase Thanks James. Yes a long road. Increasing drastically the funding for multidisciplinary basic science, including Structural Biology, Chemical Biology and Chemistry is so critical for Australia to remain internationally competitive.
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Prof Louise Purton
Prof Louise Purton@purton_louise·
It’s great to see two amazing #WomeninSTEMM in Australia, @dr_opatel @Isa_Lucet being acknowledged for their key contributions to a drug that is making a major impact in health outcomes for patients with a type of blood cell cancer. I am very proud to know them.
WEHI (Walter and Eliza Hall Institute)@WEHI_research

A fantastic achievement for a home-grown Australian discovery. Congrats to WEHI #structuralbiologists, @Isa_Lucet @dr_opatel for their contribution to structure-based #drugdiscovery of #momelotinib during their time at @MonashUni in partnership with Cytopia. #WomenInScience

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Isa Lucet
Isa Lucet@Isa_Lucet·
@WEHI_research @dr_opatel @MonashUni Privileged to have had the opportunity to contribute to such an impactful research program as a NHMRC Industry Fellow back in the days. Many thanks also to @WEHI_research for their continued support in kinase drug discovery over the past decade.
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WEHI (Walter and Eliza Hall Institute)
WEHI (Walter and Eliza Hall Institute)@WEHI_research·
A fantastic achievement for a home-grown Australian discovery. Congrats to WEHI #structuralbiologists, @Isa_Lucet @dr_opatel for their contribution to structure-based #drugdiscovery of #momelotinib during their time at @MonashUni in partnership with Cytopia. #WomenInScience
GSK@GSK

#News for #investors and #media: The @US_FDA has approved our new treatment for #myelofibrosis that may address key manifestations of the disease, namely anaemia, constitutional symptoms and splenomegaly.

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Demis Hassabis
Demis Hassabis@demishassabis·
Excited to share #AlphaMissense our new AI system that can classify whether genetic mutations (missense variants) are benign or harmful - a critical step toward uncovering causes of many diseases, from cystic fibrosis to cancer. In @ScienceMagazine today dpmd.ai/AlphaMissenseDH
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Isa Lucet
Isa Lucet@Isa_Lucet·
A shining example of innovation, showcasing the power of integrating structural biology in early drug discovery and academia/industry partnership. Kudos to the incredible teams at Monash & Cytopia. Special shoutout to the many women involved #WomenInScience
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Dr Onisha Patel
Dr Onisha Patel@dr_opatel·
From LAB to PATIENTS. Great to be part of a team with Andrew Wilks @ausmedchemist @Isa_Lucet +others on discovering #momelotinib at a little known Melbourne #drugdiscovery startup Cytopia back in early 2000. Now approved by @US_FDA for #myelofibrosis patients with anaemia 🎉 🎉🎉
GSK@GSK

#News for #investors and #media: The @US_FDA has approved our new treatment for #myelofibrosis that may address key manifestations of the disease, namely anaemia, constitutional symptoms and splenomegaly.

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Keşfet

@joshuamhardy @TonyPapenfuss @WEHI_research @CCeMMP @ONJCRI @scisignal @latrobe @LungYu_Liang