Isaac Allen

@JCO_ASCO @tischkowitz @clare__turnbull @paulpharoah @stevenhardy83 @De1Diana Finally, many thanks to my supervisor @antonis02!

@JCO_ASCO Thanks to all collaborators: @tischkowitz @clare__turnbull @paulpharoah @stevenhardy83 @De1Diana

In the latest study from my PhD & @CanGeneCanVar programme, published in @jco_asco, we looked at Risks of Second Cancers in Female and Male Breast Cancer Survivors carrying BRCA1 &  BRCA2 pathogenic variants (PVs)  using linked NHS data: Paper: doi.org/10.1200/JCO.24…

@Isaac__Allen @Cambridge_Uni Read the coverage of the article in @guardian tinyurl.com/yc24fbmf

In the largest #BreastCancer survivor cohort to date, female survivors in the poorest areas have about 35% higher risk of developing unrelated second cancers compared to those in the wealthiest areas in the UK. @Isaac__Allen @Cambridge_Uni More findings👇 thelancet.com/journals/lanep…

Congratulations @Isaac__Allen, PhD student in @antonis02 group, on this paper in @lancetRH_Europe on risks of second cancers in female and male #BreastCancer survivors, using NHS England data on ~600,000 patients in England. doi.org/10.1016/j.lane… @CRUKresearch

Latest paper from the group: On risks of second cancers in female and male breast cancer survivors, using linked EHR data on ~600,000 patients in England. In @lancetRH_Europe doi.org/10.1016/j.lane… Expertly led by @Isaac__Allen for his PhD @CRUKresearch cam.ac.uk/research/news/…

6/Thanks to all @CanGeneCanVar collaborators and co-authors, particularly @stevenhardy83 @clare_turnbull @tischkowitz @paulpharoah and @antonis02, and patients that contributed their data and funder @CRUKresearch

5/ #Female #Breast #Cancer #Survivors diagnosed when #Younger (age <50) had higher Relative Risks of second cancers.

4/ Greater #Socioeconomic #Deprivation levels were #associated with higher second #Lung cancer, #Kidney cancer, #Head and #Neck cancer, #Bladder cancer, #Oesophagus cancer, and #Stomach cancer #Risks in #female #Breast #Cancer #survivors.

3/ Highest #Cancer #Risks in #Female #BreastCancer survivors were at the #Unaffected #Breast, #Endometrium, blood - #Myeloid #Leukaemia and #Ovary. #MaleBreastCancer survivors were at higher #CancerRisk at the #Contralateral breast and #Prostate.

2/ The largest study on second cancer risks after Breast Cancer performed to date in men or women, using a novel linkage of the NationalCancer Registration Dataset and the Hospital Episode Statistics Admitted Patient Care / Outpatients data.

1/ Pleased to share a new, population-scale Second Cancer Risks analysis in male and female #BreastCancer survivors, using NHS England data, through my PhD work. doi.org/10.1016/j.lane…

@shepadore @LBC I've messaged you.